Hi Brian, thank you for your question on our Qualia NAD+ formulation. We do include Coffeeberry® in our NAD+ formulation which s made from organic coffee fruits, which are often called coffee cherries. Like cherries, coffee plants produce soft red fruits surrounding a pit or hard seed. The seed (or coffee “bean”) is roasted to make coffee. But it’s the fruit that is being used to make Coffeeberry®. It does this by promoting arousal (wakefulness), which is a necessary ingredient for being able to pay attention and react quickly. Not surprisingly, this has led to caffeine being one of the most widely used and studied substances for supporting both sports performance and brain function. While caffeine gets most of the attention, coffee polyphenols support healthy function. Most nootropics use pure caffeine; a better approach is using a coffee extract that gives caffeine and the naturally occurring coffee fruit polyphenols. Qualia NAD+ contains 28 mg of caffeine. While this amount is less than the caffeine in, for example, a 12-ounce Coke, it is enough that it may disrupt sleep in some people if taken later in the day.