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Qualia Senolytic contains a combination of nine vegan ingredients and was formulated to be taken on two consecutive days once a month. It was created to support healthy aging in an area called “cellular senescence.”* But what is that?
Aspects of cellular structure and function gradually shift in certain predictable ways as a normal part of the aging process. Scientists refer to nine of these gradual shifts as the Hallmarks of Aging—think of a hallmark in this case as meaning a distinguishing characteristic. Cellular senescence is one of the nine characteristics; it has to do with a special type of stressed or worn out cell called a senescent cell.
Senescent cells are created and removed from tissues constantly throughout life. They are formed as a routine part of normal healthy function. Muscle tissues, as an example, create senescent cells after intense exercise as part of recovery.
Senescent cells are also formed when a cell becomes so stressed or worn out that it’s not worth putting in cellular work to maintain or repair it (replacing it would be a better use of cellular resources).
As we get older, healthy creation and removal functions tend to shift in ways that result in gradual increases in the proportion of senescent cells in some, often many different tissues—removal functions fall behind. This occurs for two main reasons.
Senescent cells should proceed through a series of molecular steps in a biological process that got its name from the Greek word for “falling off,” in the sense of ripe fruit falling from trees, leaves falling from a plant, or petals falling from flowers.
Some senescent cells can get sidetracked on the journey to “falling off” (in this case from our tissues). These cells become experts at surviving, exploiting normal cellular prosurvival functions to linger, loitering and taking up space in tissues. This would be somewhat analogous to yellowing leaves that haven’t fallen off a plant yet.
Because it’s normal to have some senescent cells start, but not complete the “falling off” journey, tissues need a back up plan. The backup plan is the immune system, which should act a bit like a gardener who prunes away the yellowing leaves on a plant.
One of the jobs of the immune system is to find loitering senescent cells and remove them. When the immune system is adept at finding and removing these cells, the pace of removal maintains a healthy balance with creation. This is where aging enters the story.
When we are young, the immune system will typically be great at finding, and figuratively speaking, pruning away senescent cells. As we get older, the immune system tends to gradually become less proficient in lots of different ways; one of these is finding and pruning senescent cells—some senescent cells may get missed. Over time, this can result in gradual accumulation of senescent cells.
Senescent cells are often described as being “zombie cells.” This is because, not unlike the undead zombies in movies, a senescent cell can get stuck in a kind of limbo. It has one more thing in common with movie zombies: senescent cells can convince otherwise healthy cells to become senescent cells, which may add to the accumulation burden.
But why is the accumulation of senescent cells important? It comes down to a fundamental principle—the health of tissues depends on the health of the cells in those tissues. What do you think might happen if space that should be filled with healthy cells is being taken up by loitering senescent cells instead? The answer is very similar to what occurs if a plant has a growing number of yellowing leaves taking up space on its branches.
There are a few main reasons gardeners prune leaves: (1) pruning allows resources and nutrients to be used in healthy, vibrant leaves rather than being poorly invested in less healthy ones; (2) pruning encourages new growth; and (3) pruning promotes the overall health and appearance of a plant. This is where senolytics come in; they can be thought of as a way to prune away the equivalent of yellowing leaves in our tissues.*
The word “senolytic” is derived from the Latin words senex (=old) and lytic (=destroying). They are aptly named. Senolytics have an affinity for finding cells that are using senescent cell prosurvival mechanisms, and then convincing them to finish the journey to “falling off” instead.*
Now let’s answer the original question—What is Qualia Senolytic? It is a dietary supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. It does this by, figuratively speaking, pruning away senescent cells. Its goals are similar to those of pruning a plant: support efficient use of cellular resources, encourage growth of more youthful cells by making “room” in tissues for them, and ultimately to support tissue health and appearance—promoting whole-body rejuvenation.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
Qualia Senolytic is intended to be a great complement to other Qualia products, especially the first product we created in our longevity line, Qualia Mitochondria+. To get the most out of Qualia Mitochondria+ we recommend that you take Qualia Mitochondria+ throughout the month.
Behaviors and strategies that support immune system performance would be expected to also complement senolytics.* We recommend focusing on: (1) Consistently getting enough quality sleep—sleep is a major determinant of how well the immune system performs; (2) Regularly exercising in ways that create fitness—being sedentary and excessive exercise can both weaken immune performance (think Goldilocks principle when it comes to exercise); (3) Managing stress—higher stress is hard on the immune system; and (4) Practicing some type of fasting behavior for several days every three months or so—Valter Longo’s (interviewed on Collective Insight Podcast) fasting-mimicking diet is an example of one of these approaches; it helps rejuvenate immune cells*. And, of course, eating a healthy diet is important for immune system health and complements senolytic supplement protocols.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
The aspects of healthy function that Qualia Senolytic may influence can vary person-to-person: for some people it may be the skin, for other people it may be fat or muscle tissue, for others it could be the brain, joints, immune system, etc. Because of this, there is no one way that Qualia Senolytic is experienced.* With the above in mind, the areas you should expect benefits are the areas that are typically most impacted during aging, so pay attention to signs of healthier skin, muscles, joints and brain functions, as well as overall health and energy, after two-to-three months of taking Qualia Senolytic.*
Some of the potential side effects of taking Qualia Senolytic include light headaches, lack of energy, slight irritability, gastrointestinal disturbances, and other mildly unpleasant symptoms. To mitigate these effects, we recommend eating food and drinking extra water during the two-day Senolytic treatment period.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
We recommend taking all 6 capsules of Qualia Senolytic one day, and the following day, take the other 6 capsules. It doesn't matter if you take them all at once or spread throughout the day.
Our general recommendation is to take Qualia Senolytic with food. The reason for this recommendation is because (1) with food is the most common way senolytics have been used in studies, and (2) Qualia Senolytic contains concentrated food extracts, some of which may be more bioavailable if taken with food.
We would also recommend drinking some extra water during the two day treatment.
Qualia Senolytic is also intended to be a great complement to other Qualia products, especially the first product we created in our Longevity line, Qualia Mitochondria+.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
Qualia Mitochondria+ was formulated to support cells in making energy and keeping healthy cells healthy through the aging process. It's something designed to be taken on most days of the month. Qualia Senolytic was formulated to support pruning away of unhealthy cells as we age. It's something designed to be taken two days a month. We consider them to be perfect complements, with Qualia Senolytic being taken on a couple of the monthly off days from Qualia Mitochondria+.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
Qualia Senolytic should be thought of as a product that pays healthy aging dividends over time and with repeated cycles of use.
In the pilot study we did of Qualia Senolytic prior to bringing it to market, the participants were between the ages of 32 and 66 and had at least a moderate degree of difficulty in comfortably performing a variety of activities of daily living (this is something that frequently accompanies aging).
Most of the participants reported greater ease in comfortably performing these activities and less of the occasional stiffness that can accompany aging after two dosing cycles of Qualia Senolytic (i.e., after taking a full dose of Qualia Senolytic for 2 days, taking a few weeks off, and then taking another full dose of Qualia Senolytic for 2 days).*
While this is one use case, we created a senolytic supplement like Qualia Senolytic to support healthy aging in many areas (brain, muscles, immunity, joint, skin, etc.) so benefits may show up at varying speeds and in a variety of areas of function in different people depending on where aging is taking a toll.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
Yes. While our general recommendation is to take 6 capsules a day on the 2 days a month we recommend that you take Qualia Senolytic, it’s perfectly fine to take a lower dose. But the trade-off of taking a lower dose is getting less senolytic support, which may be just right for a younger, lighter weight, or very healthy adult, but may be sub-optimal support for an older, heavier, or less healthy person, as an example.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease
Intermittent use—some experts call this a “hit and run” approach—is the way senolytic supplements are most commonly used to support healthy aging.* The “hit and run” approach means that senolytics are recommended to be taken for a couple of days followed by a longer period of time when they are not taken.
Senescent cells are created in, and removed from tissues constantly throughout life (and over shorter periods of time like a month). The goal of taking senolytics is to shift the balance in favor of removal, which should not require daily dosing since senescent cells accumulate slowly.*
Think about this “hit and run” dosing as being a bit like how you might approach pruning a plant: pruning is something you’d want to do frequently but not every day. Another way to think about taking senolytics is as being akin to a water fast or detox protocol, which are not something done every day, but instead, would be something done for a few days periodically to support health goals.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
Qualia Senolytic is designed to support healthy aging by targeting and clearing senescent cells—damaged cells that no longer function properly but remain in the body. Benefits may include increased energy, reduced feelings of fatigue, support for tissue repair, and overall rejuvenation. By helping remove these “stagnant” cells, it aims to promote vitality, mobility, and healthier cellular function.*
Foods rich in natural senolytics—compounds that help clear out senescent or “zombie” cells—include those high in fisetin, quercetin, and resveratrol. Examples are berries (like strawberries and blueberries), apples, cruciferous vegetables (such as broccoli and kale), leafy greens, dark chocolate, fatty fish, and plant-based sources like green tea, turmeric, ginger, and long pepper.
However, although there are many different fruits, vegetables, herbs, spices, and other types of foods in the diet that contain senolytic or senomorphic compounds, no food source has been shown to contain senolytics in sufficient amounts for actual senolytic benefits, so far. In other words, in research studies, these compounds showed senolytic action (i.e., they were able to promote the death of senescent cells) only at amounts that are much higher than those available in foods.
By our late 20’s, most of us will begin noticing changes caused by getting older. By our 40’s, we’ve gone beyond noticing …many of us are feeling aspects of the aging process.
Some scientists believe that one of the reasons we notice and feel some aspects of (unhealthy) aging is because of stressed or worn out cells called senescent cells.
Qualia Senolytic was formulated to support tissues in pruning away these senescent cells. Because senescent cells tend to gradually accumulate with the passing of years, senolytic supplements like Qualia Senolytic was created for adults in their 40’s and older or younger adults who may already be noticing or feeling the aging process.*
Qualia Senolytic can also be taken periodically to support adults of all ages in managing senescent cells (AKA zombie cells) as a way to proactively promote healthy aging.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.