Products

Qualia Senolytic is formulated to help bring the creation and removal of senescent cells (sometimes called "zombie cells") back into a healthy balance. Senescent cells are older cells that have stopped dividing but remain in the body, where they can negatively affect tissue health and appearance. Qualia Senolytic supports the body’s natural process of “pruning” these cells, similar to how a gardener removes yellowing leaves to promote new growth and overall plant health. The goal is to support efficient use of cellular resources, encourage the growth of more youthful cells, and promote whole-body rejuvenation. Clinical studies have shown that Qualia Senolytic can significantly reduce joint discomfort and may provide additional benefits for physical function and overall vitality.

Qualia Stem Cell is designed to support stem cell health by addressing the hallmark of aging known as “Stem Cell Exhaustion.” This formula combines botanicals, nutrients, and superfoods to activate and nourish stem cells, supporting their mobilization, migration, proliferation, and differentiation. The product is intended to promote healthy levels of circulating stem cells and support their activation and maintenance, which are essential for tissue healing and healthy aging. Over long-term use, benefits may include support for skin, hair, joints, muscles, cognitive function, and overall vitality. Qualia Stem Cell is typically taken for 4 consecutive days each month to mimic a healthy physiological healing response.

Can they be taken together? Yes, Qualia Stem Cell was designed to complement Qualia Senolytic, and they can be taken together as part of a comprehensive approach to healthy aging. There are no known negative interactions between these two products. Advantages of each:

1. Qualia Senolytic: Focuses on removing senescent cells to make room for healthier, more youthful cells, supporting tissue health and rejuvenation.

2. Qualia Stem Cell: Supports the activation and maintenance of stem cells, which are crucial for tissue repair, regeneration, and overall vitality.

Taking both products together may provide a synergistic approach: Qualia Senolytic helps clear out old, non-functional cells, while Qualia Stem Cell supports the replenishment and activation of new, healthy cells. This combination can be especially beneficial for those interested in comprehensive support for healthy aging and tissue rejuvenation.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

This doctor-formulated, premium formula combines 16 herbal extracts, superfoods, and stem cell nutrients to: (1) support stem cell activation through facilitation of the mechanisms that drive cellular rejuvenation – stem cell mobilization, migration, proliferation, and differentiation; and (2) support stem cell maintenance through the stimulation of mechanisms that optimize long-term stem cell health – self-renewal and survival.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Stem cells spend much of their time in a dormant or resting state—inactive but poised to respond when we need them. Think of this as a bit like being asleep. Qualia Stem Cell was formulated to “activate” stem cells, in essence waking some of them from this resting state to support healing and healthy aging. Rather than “waking up” stem cells every day of the month, we think it makes more sense to support them in being more active in short bursts of time to more closely mimic a healthy physiological healing response.

Stem cells spend much of their time in a dormant or resting state—inactive but poised to respond. Activation is a general way to refer to the non-resting state. The first step in activation is mobilization, which means moving stem cells from where they are resting into circulation. After being mobilized, stem cells need to carry out additional mechanisms to become specialized tissue. In the scientific literature, these mechanisms are called migration (to the tissue of interest), proliferation (expand cellular numbers), and differentiation (become the new tissue). The four primary actions described here (mobilization, migration, proliferation, differentiation) can collectively be summarized as stem cell “activation.”*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

It's okay for individuals to take Qualia Stem Cell less often than once a month if they prefer, but the trade-off is receiving less stem cell support for tissue healing and healthy aging. Taking Qualia Stem Cell monthly is the dosing approach we recommend for adults of all ages who are beginning to notice or experience signs of aging and want support for healthy aging. This approach is intended to provide the ongoing support to offset the gradual stem cell exhaustion that is a hallmark of aging. Once a quarter can be a good option for younger individuals (aged <30) or those not yet feeling the effects of aging, who want to proactively support healthy aging through stem cell support.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell can be taken by adults (aged 18+) wanting to support stem cell health and youthful tissue repair & rejuvenation. As always, we recommend consulting with your physician prior to use if you are taking any medications, or have any diagnosed medical conditions.

We recommend adults (aged 18+) take 6 capsules daily for 4 consecutive days out of every month.

Yes, less than 6 capsules is fine, but this lower serving size may provide less stem cell health benefits and less overall support for youthful cellular & tissue repair.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell should not be taken by children or teenagers, as it was designed to support healthy aging in adults (18+).

Women who are pregnant or nursing.

Children and teenagers under the age of 18.

Anyone with an allergy to bee products (Qualia Stem Cell contains royal jelly).

Check with your doctor before taking Qualia Stem Cell if…

• you are currently taking any prescription medications—some medications may interact with ingredients in Qualia Stem Cell.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

Over long term use of Qualia Stem Cell (3+ months), it is possible to see rejuvenation in these key areas: (1) support for skin, (2) support for hair, (3) support for joints, (4) support for muscle and tendon, (5) support for cognitive function, (6) support for overall vitality.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell can be taken with or without food.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell can be taken at any time of the day, but our general recommendation is to take the suggested serving size in the morning.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

The core botanicals promoting optimal circulating stem cell levels are branded ingredients (CyanthOx™, AFAninPlus®, Aloemac®) with clinical studies suggesting that an increase in stem cell numbers occurs within 3 hours after consuming the product. The timeline for seeing benefits after this initial increase in numbers and subsequent rejuvenation processes can vary significantly depending on individual factors, but it could take up to several months to begin to notice benefits. Qualia Stem Cell is a product that should be thought of as something that provides more benefit with repeated cycles of use.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Stem Cell was designed to complement Qualia Energy Shot®.

Yes. Qualia Stem Cell was designed to complement Qualia Mitochondria+.

At the doses provided in this supplement, there are no known interactions between any of the ingredients in Qualia Stem Cell and alcohol.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes, Qualia Stem Cell can be taken while intermittent fasting. We do not expect this formula or any of its ingredients to interrupt an intermittent fast.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell is a cutting-edge product designed to support stem cell health by targeting both key aspects of the hallmark of aging “Stem Cell Exhaustion” – reduced stem cell numbers and function. This formula combines time-tested botanicals known for supporting vitality and longevity, nutrients & superfoods to activate and nourish stem cells, and a Traditional Chinese Medicine blend of herbs & compounds for supporting tissue healing. Qualia Stem Cell’s superior ingredients work together to promote healthy levels of circulating stem cells and support their activation and maintenance, directly addressing this hallmark of aging for a more youthful you.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Stem Cell was designed to complement Qualia Mind®.

It’s fine to take Qualia Stem Cell with your first meal of the day rather than earlier in the morning.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Stem Cell was designed to complement Qualia Magnesium+.

We recommend storing Qualia Stem Cell in a cool dry place, but it does not need to be refrigerated.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Stem Cell was designed to complement Qualia Senolytic®.

Yes. Qualia Stem Cell was designed to complement Qualia Probiotic+.

Yes. Qualia Stem Cell was designed to complement Qualia Joint Health™. 

Yes. Qualia Stem Cell was designed to complement Qualia NAD+®.

Since this supplement mainly contains concentrated extracts rather than whole foods, its caloric content is minimal. Yeast beta-glucans and fucoidan are indigestible carbs with negligible calories, royal jelly powder has small amounts of proteins and carbs, and L-serine provides a tiny calorie contribution. Although exact data isn’t available, we estimate a six-capsule serving of Qualia Stem Cell contains about 7.5-10 calories.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

There are no supplement ingredients that are known to interact negatively with Qualia Stem Cell. However, please check with your doctor before starting any new supplement regimens.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

If you notice something you think may be a side-effect, please stop taking Qualia Stem Cell and let us know by email or by calling or texting (855) 281-2328.

There are no special instructions for getting started. Our general recommendation is to simply start by taking 6 capsules with water or a beverage of your choice with or without food.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

We recommend taking Qualia Stem Cell daily for 4 consecutive days on a monthly basis, but how you do this is up to you. Some people may prefer to take three capsules of Qualia Stem Cell twice a day at different meals, while others like to take all six capsules at once.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Our general recommendation for Qualia Stem Cell does not take body weight into account, because the clinically studied ingredients in the formula have been given at the same amounts to people of all body weights in human studies on them. But it is perfectly fine to adjust the dose lower for any reason, including body weight.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Stem Cell has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

Qualia Stem Cell is gluten free, non-GMO, and vegetarian, but is not vegan. The royal jelly powder is a bee product, which is typically not considered vegan.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes, it’s fine to take three capsules earlier and three capsules later in the day.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Stem Cell was designed to complement Qualia Night®.

Yes. Qualia Mind® Caffeine Free can be taken with Qualia Skin®.

Yes. Qualia Mind® Caffeine Free can be taken with Qualia Senolytic®.

We recommend taking Qualia Mind® Caffeine Free 5 days a week. These days can be all in a row or broken up in a way that best matches your needs and preferences.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

No, our suggested amount of Qualia Mind® Caffeine Free does not take body weight into account, but it is perfectly fine to take a lesser amount for any reason, including body weight.  

We recommend storing Qualia Mind® Caffeine Free in a cool dry place but not a refrigerator. Refrigeration promotes moisture condensation after a bottle has been opened, so is not recommended for storing the bottle—moisture is more of a problem for shelf-life in the ingredients in Qualia Mind Caffeine Free than room temperature heat.

If you notice something you think may be a side-effect, please stop taking Qualia Mind® Caffeine Free and let us know by email or by calling or texting (855) 281-2328.

Several ingredients in Qualia Mind® Caffeine Free—Rhodiola, Ginkgo, PQQ, Lutein, Phosphatidylserine, and Nutricog®, as examples—can be thought of as more akin to the tortoise than the hare from Aesop’s fable (i.e., “slow and steady wins the race”). In other words, they support cognitive performance after steadily taking them for a sustained period of time. So, we recommend taking Qualia Mind Caffeine Free for at least 2 months for best results. It’s also good to keep in mind that, in general, best responses to nootropics are expected when a person consistently gets sufficient sleep, adequate exercise, and eats a balanced diet.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

We do not recommend giving Qualia Mind® Caffeine Free to children or teenagers. Because there isn’t enough reliable information on the use of every ingredient in the formula in children and teenagers, we caution against using it in these age groups.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® Caffeine Free was developed to support: (1) mental energy & alertness; (2) attention, focus & concentration; (3) motivation & productivity; (4) learning & memory; (5) the ability to expend more mental effort for longer periods of time; (6) and resilience to stress.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® Caffeine Free 2.0 - What's Changed? How's It Different?

We’re launching a new and improved Qualia Mind® Caffeine Free! As we did with Qualia Life® 2.0, Qualia Mind Caffeine Free 2.0 builds on and improves upon the original version while keeping the backbone of the formula the same. We’ve been keeping track of the feedback we receive from our community, the latest research, and new ingredients made available since we first launched Qualia Mind Caffeine Free: we took this and more into account when we designed this upgrade.

Our goals for Qualia Mind Caffeine Free 2.0 were ambitious. We wanted to make a great nootropic even better. We wanted to find out if we could succeed in doing this with fewer capsules. We wanted to add nutritional support for brain areas that were not as well supported with the original Qualia Mind Caffeine Free, such as hearing and vision.* This required more than simply making slight changes to what’s in Qualia Mind Caffeine Free; it was a more extensive reformulation. We added 13 new ingredients. To make room for them, 8 ingredients needed to be removed, and the amounts of several others changed, with some increasing and some decreasing.

Here’s what’s changed and why. 

We Have More Ingredients in Fewer Capsules 

One of our goals was to decrease the number of capsules in a serving of Qualia Mind Caffeine Free without compromising quality. We know that taking so many capsules can be fatiguing for some people—it’s a comment we get a lot. But the fact is that what we see as the defining feature of Qualia Mind Caffeine Free—a comprehensive support of neural pathways and processes that promote brain health and cognitive performance—is contingent on supplementing a high number of ingredients. To be able to target so many different aspects of brain function and performance, we need sufficient amounts of the ingredients that do so—and that inevitably means a relatively high capsule count.* Decreasing the number of capsules was not an easy task given our formulation approach, but we pulled it off!

In fact, in Qualia Mind Caffeine Free 2.0, we managed to decrease the number of capsules per serving from 7 to 6, while also increasing the number of ingredients from 27 to 32. That means added benefits in fewer capsules!*

We Have More Trademarked Ingredients

The number of branded ingredients in Qualia Mind Caffeine Free has increased from four in Mind 1.0 to eight in the new and improved Mind 2.0! 

Branded ingredients are ingredients that a supplier has gone to the effort and cost of trademarking. This is typically done to associate the brand name of the ingredient with claims of specific health benefits or higher quality. Often their development involved significantly more research and expense than non-trademarked (i.e., generic) ingredients. Because of the high R&D investment, branded ingredients are usually more expensive than generic ingredients. But the extra cost can be worth it because sometimes they are just that much better.* 

Having more trademarked ingredients is one of the ways the new Qualia Mind Caffeine Free delivers even more value to you.*

We Included Up-and-Coming Nootropics

In the 6 plus years since Qualia Mind Caffeine Free 1.0 launched, science has continued its march forward. There’s been new research. Some ingredients have appeared on the market that weren’t available before. Self-experimentation and N of 1 use has given insight into use of some nootropics and how they combine with other ingredients. Put simply, the nootropic community has not been static; we did not want Qualia Mind Caffeine Free to be either. 

We consider ingredients like Nutricog® (a Terminalia chebula fruit extract and Boswellia serrata gum resin extract), Sabroxy® (Oroxylum indicum bark extract), and Polygala tenuifolia Root Extract as being rising stars in the nootropic community. We’re confident these ingredients will become more popular as more people learn about and experience them. You get to experience them today in Qualia Mind Caffeine Free 2.0. 

We Brought Back Some Old Favorites

Before Qualia Mind, there was Qualia—the first nootropic formula we launched went by the name Qualia. It was supplied in two bottles, with instructions to take capsules from one of the bottles away from food first thing in the morning and capsules from the other bottle with breakfast (or food). This was a bit complicated for some people. This two-bottle formula was also a lot of capsules, with a full serving size of 11 capsules between both bottles.

To get from the 11 capsules in original Qualia to the 7 in Qualia Mind Caffeine Free 1.0 required removing some ingredients. Lion’s Mane extract was one of these removals. Magnesium was another.  Both ingredients offer support for a healthy brain. Both are also among the nootropic communities favorites.* We’re excited to be able to offer both again as part of Qualia Mind Caffeine Free 2.0.

We Included “Underappreciated” Nootropics

Nootropic ingredients can be thought of as some being underrated (they don’t get enough credit or appreciation), some being properly rated, and some being overrated. The overrated nootropics get used a lot; maybe more than they deserve. The underrated ones get overlooked. We wanted to correct this in Qualia Mind Caffeine Free 2.0.

After reviewing an extensive amount of research and following what real world users experience, we think a strong and compelling argument can be made that Lutein and Zeaxanthin (supplied as Lutemax® Brain), Saffron, and Boron fall into the underrated category. They’ve been included in Qualia Mind Caffeine Free 2.0. And, despite Celastrus paniculatus Seed Extract having been in Qualia Mind Caffeine Free since it was first launched, we consider this as being another underrated and underappreciated nootropic—it’s on the very short list of our favorites. In Qualia Mind Caffeine Free 2.0, we increased the amount of Celastrus by 50% (from 60 to 90 mg) and include it as SmartSeed™, an extract that is made specially for us.* 

We Added More Brain-Essential Nutrition*

Brain nutrients are compounds naturally found in the brain and used to support its structure and function. Qualia Mind Caffeine Free 1.0 had 17 brain nutrients; Qualia Mind Caffeine Free 2.0 has 21.* 

Qualia Mind Caffeine Free 1.0 included most of the B complex vitamins, but Qualia Mind Caffeine Free 2.0 supplies them all. So in addition to the B vitamins already found in Mind Caffeine Free 1.0—Thiamine (as Thiamine HCl), Niacin (as Niacinamide), Pantothenic Acid (as Calcium Pantothenate), Vitamin B6 (as Pyridoxal 5'-Phosphate), and Vitamin B12 (as Methylcobalamin)—Mind Caffeine Free 2.0 also includes Riboflavin, Biotin, and Folate (as L-5'-Methyltetrahydrofolate Calcium). Every B vitamin is either a cofactor or a precursor for a cofactor in a key metabolic process and all have essential roles in cellular metabolism, energy production, and brain health.* 

We also added two minerals involved in brain function to Qualia Mind Caffeine Free 2.0: Magnesium (as Magnesium Aspartate) and Boron (as Boron Glycinate). Finally, we added the macular carotenoids Lutein and Zeaxanthin (from Lutemax® Brain), which are found in high amounts in the retina and the brain where they have antioxidant defense functions.*

We maintained the neurotransmitter precursors L-tyrosine (as N-Acetyl-L-Tyrosine, for dopamine support), Citicoline (as Cognizin®), Alpha-GPC (both for acetylcholine support); the membrane phospholipid Phosphatidylserine; the brain amino acid neuromodulator Taurine; the mitochondrial nutrients Pyrroloquinoline Quinone (PQQ) and Acetyl-L-Carnitine; and the antioxidant and neuroprotection-supporting vitamins Vitamin C (as Ascorbic Acid) and Vitamin D (as Cholecalciferol from VegD3®).*

We removed DL-Phenylalanine (an amino acid and dopamine precursor that had some redundancy with N-Acetyl-L-Tyrosine), Docosahexaenoic Acid (DHA, an omega-3 fatty acid found in membranes), and Uridine Monophosphate (a nucleotide that participates in the phosphatidylcholine synthesis pathway) (see why below) to make room for the new ingredients and as part of the solution to fewer capsules.*

We Added More Cognitive Support*

Qualia Mind Caffeine Free 2.0 provides upgraded support for several aspects of cognitive performance.* 

We upgraded memory support in Qualia Mind Caffeine Free 2.0 by increasing the amount of Ginkgo biloba Leaf Extract from 50 mg to 120 mg. The increase to 120 mg matches an amount commonly used in clinical studies where Ginkgo has supported memory (and other aspects of cognition) in both older and younger adults. We also added Lutemax Brain Marigold Flower Extract, a source of the macular pigments Lutein and Zeaxanthin. These macular pigments, in general, and Lutemax specifically, have supported memory and markers of neuroplasticity in clinical studies. Furthermore, we added Nutricog®, a blend of Terminalia chebula Fruit Extract and Boswellia serrata Gum Resin Extract that supports memory as well as learning rate and capacity—this added support for learning is a new addition to Qualia Mind Caffeine Free.* 

In addition to supporting cognitive performance, Ginkgo biloba also has adaptogenic actions—it supports healthy stress responses and a calm mood. Therefore, by increasing the amount of Ginkgo biloba, Qualia Mind Caffeine Free 2.0 also upgrades its support of cognitive performance under stress. This upgrade was reinforced by adding Polygala tenuifolia Root Extract, another herb that supports healthy stress responses. Further contribution to this upgrade comes from also increasing the amount of Rhodiola rosea Root Extract, a well-known adaptogenic herb, from 300 mg in Qualia Mind Caffeine Free 1.0 to 370 mg in Qualia Mind Caffeine Free 2.0. This increase in the amount of Rhodiola rosea adds more support for mental energy and resistance to mental fatigue, further contributing to supporting the capacity for mental work under stress or fatiguing circumstances.*

We Added Support for Vision and Hearing

Vision and hearing are important for cognitive performance and maintaining cognitive health. Therefore, we wanted to include support for these key functions in Qualia Mind Caffeine Free 2.0. 

One of the main factors contributing to the deterioration of visual health is oxidative stress in the retina. The  blue light emitted by screens is an example of an eye stressor. We added Lutein and Zeaxanthin (as Lutemax Brain Marigold Flower Extract) because these are antioxidant pigments that absorb excess blue light. These pigments accumulate in a central area of the retina called macula (which is why they’re called macular pigments or macular carotenoids). Lutein and Zeaxanthin must be obtained from the diet and adequate dietary levels are essential for a healthy visual response to blue light.

We also included Saffron Stigma Extract because it provides eye-healthy carotenoids and supports antioxidant defenses in the eye, retinal function and health, and visual acuity. Two ingredients that were already part of Qualia Mind Caffeine Free 1.0 also support vision: Vitamin B12 as Methylcobalamin supports healthy nerve function and may help to support optic nerve health, which carries visual information to the brain; and Taurine is the most abundant amino acid in the retina, where it is essential for the light-capturing function of photoreceptors, acts as an antioxidant, and supports protection against stress from blue light and ultraviolet light.* 

Taurine is also found in the cochlea, the part of the inner ear involved in hearing, where it supports auditory neurons, neuroprotective functions in the cochlea, and auditory health. In Qualia Mind Caffeine Free 2.0, we added magnesium as Magnesium Aspartate because it is a form that has been used in several clinical studies for supporting healthy hearing and resilience from noise stress. Pyrroloquinoline Quinone (PQQ) also offers support for hearing (read about vision and hearing support in Qualia Mind: The Building of a Nootropic Stack).*

We Added enXtra® as a Caffeine Replacement

enXtra® is a clinically studied and standardized Alpinia galanga rhizome extract, which is part of the ginger family. Because Alpinia galanga has shown the ability to promote central nervous system activity and to support healthy acetylcholine and dopamine signaling, enXtra® may provide some of the benefits you’d get from caffeine. In clinical studies, supplementation with enXtra® has primarily been experienced as supporting alertness and the attention network.* We selected enXtra as the replacement for caffeine, because it is a non-caffeine way to support neurotransmitter functions involved in mental alertness. While the amount used in human studies has been 300 mg, because enXtra is taking the place of ingredients that collectively contributed about 150 mg to the overall formula, there was only capsule space to include half the amount of enXtra used in the human studies. We expect this amount to play a supportive and complementary role with the other ingredients that support alertness and focus in the formula.*

What Was Removed and Why?

Improving Qualia Mind Caffeine Free meant adding new ingredients. These new ingredients were competing for the capsule space with existing ingredients. Improving the formula, while also decreasing the number of capsules, meant the competition was fierce. Put simply, some of the ingredients that were in Qualia Mind Caffeine Free 1.0 were outcompeted. It doesn’t mean we don’t like these ingredients, but to add the upgrades we made, some ingredients needed to be subtracted. 

Docosahexaenoic Acid (DHA) was removed for a few reasons. DHA is responsible for a mild “fishy” smell in Qualia Mind Caffeine Free 1.0 that many customers have commented on—removing DHA solves that issue. Similar to Qualia Mind Caffeine Free 2.0, the competition for capsule space in Mind Caffeine Free 1.0 was fierce. Because of this competition for capsule space, while we included DHA in the original Qualia Mind, Caffeine Free we were only able to fit a modest amount in a serving. As a company, we strive to ensure that, when an ingredient is used in a formula, the amount is sufficient. The amount of DHA being included may not have been living up to this standard, so that was another reason that weighed into removing it. A third reason for removing DHA was because it is not an ingredient that would be expected to support short-term nootropic benefits—you often need to take it daily for a long time before cognitive effects are experienced. DHA was included in Qualia Mind Caffeine Free 1.0 as an investment in long-term brain health. DHA is the most abundant omega-3 fatty acid in the brain, where it is a main structural component of the neuronal cell membrane and supports cell signaling functions. We concluded that we could maintain membrane structural support with our existing and new ingredients, many of which have antioxidant properties that support the protection of membranes against oxidative stress, one of the main threats to membrane health.* 

Uridine Monophosphate was included in Qualia Mind Caffeine Free 1.0 in large part because of studies where it had been complementary with DHA. Its roles in the original formula were related to support for choline levels and brain membrane phospholipids. We decided to remove Uridine Monophosphate for a few reasons: First, Qualia Mind Caffeine Free includes two ingredients that provide a more direct support of choline levels—Alpha-GPC and Citicoline as Cognizin®—so we felt we had that covered. Second, following ingestion, citicoline yields choline and cytidine, with some of the latter being converted into uridine in humans, so we still have some indirect uridine support in Qualia Mind Caffeine Free 2.0. And finally, in preclinical studies, Uridine Monophosphate was often combined with DHA, and the combo was shown to support memory. So we felt that removing DHA could impact the benefits of Uridine Monophosphate. Furthermore, although Uridine Monophosphate is a nootropic ingredient appreciated among neurohackers, it is still poorly studied at the clinical level for cognitive support.* After weighing these factors, we felt that the capsule space taken up by Uridine Monophosphate could be better used by ingredients with stronger evidence of cognitive support (read about choline support in Qualia Mind: The Building of a Nootropic Stack).

DL-Phenylalanine, N-Acetyl-L-Tyrosine, and Mucuna Pruriens Seed Extract (a source of L-DOPA) were included in Qualia Mind Caffeine Free 1.0 to support the dopamine synthesis pathway which progresses from L-Phenylalanine → L-Tyrosine → L-DOPA → Dopamine. Our goal was to provide all three precursors for full dopamine synthesis pathway support. For Qualia Mind Caffeine Free 2.0, we decided to focus specifically on the rate-limiting step of the pathway, i.e., the step that determines the rate at which dopamine synthesis progresses: the conversion of L-tyrosine to L-DOPA by the enzyme tyrosine hydroxylase. Because this step can act as a bottleneck in the pathway, we figured that increasing the support for this step could be as beneficial as providing all the precursors (if not more beneficial!). Therefore, we removed DL-Phenylalanine and Mucuna Pruriens from the formula and maintained only the precursor used in the rate-limiting step: L-tyrosine (as N-Acetyl-L-Tyrosine); we also upgraded our support for the activity of the rate-limiting enzyme by increasing the amounts of two ingredients that support it—Rhodiola rosea Root Extract and Ginkgo biloba Leaf Extract—and adding another—Saffron Stigma Extract. And to further increase dopamine support in Qualia Mind Caffeine Free 2.0, we added ingredients that promote the availability of dopamine in synapses and neurons by supporting balanced dopamine reuptake and breakdown (which Rhodiola and Saffron also support), including Oroxylum indicum bark extract (as Sabroxy®), Polygala tenuifolia Root Extract, and Terminalia chebula Fruit Extract (in Nutricog®) (read about dopamine support in Qualia Mind: The Building of a Nootropic Stack).*

Bacopa monnieri Extract, which was included in Qualia Mind Caffeine Free 1.0 primarily to support cognitive function and mood, was replaced in Qualia Mind Caffeine Free 2.0 with Nutricog®,  a blend of Terminalia chebula Fruit Extract and Boswellia serrata Gum Resin Extract. The clinical study with Nutricog® indicates that it may provide stronger benefits for memory and learning, support a wider range of cognitive areas, and provide noticeable cognitive support in a shorter time frame.*

One of the great benefits users of Bacopa often report is its adaptogenic properties and ability to foster a feeling of calm and thereby support cognition in contexts of stress. To ensure that Qualia Mind Caffeine Free 2.0 not only maintains that benefit but actually upgrades it, we increased the amount of our main adaptogenic ingredient: Rhodiola rosea Root Extract. We also increased the amount of Ginkgo biloba Leaf Extract and added Polygala tenuifolia Root Extract and Terminalia chebula Fruit Extract (in Nutricog®), which have all been shown to support adaptogenic mechanisms.*

Artichoke Leaf Extract and Coleus forskohlii Root Extract were included in Qualia Mind Caffeine Free 1.0 as a combo to support long-term potentiation (LTP, a neural mechanism of synaptic plasticity involved in learning and memory) by supporting cyclic adenosine monophosphate (cAMP), an intracellular signaling molecule (through Coleus) and phosphodiesterase-4 (PDE4), the enzyme that hydrolyzes cAMP (through Artichoke), as both molecules are involved in LTP. This benefit is only hypothetical and based on in vitro studies with each extract showing the referred mechanisms of action; there are no studies showing that their combination does indeed promote LTP. This does not mean it doesn’t, but because there’s no scientific evidence to support it, we decided to remove Artichoke and Coleus forskohlii and replace them with ingredients that have actually been shown to promote LTP in preclinical research: Saffron Stigma Extract, Polygala tenuifolia Root Extract, and Lion’s Mane Mushroom (as RealLionsMane™). Supporting LTP is a means to an end. The end, in this case, is optimal learning and memory.  We thought it made sense to focus more attention on the “end” rather than the means to the end, which led to an ingredient that has been shown to support learning and memory: Nutricog® (Terminalia chebula fruit extract and Boswellia serrata gum resin extract) (read about LTP support in Qualia Mind: The Building of a Nootropic Stack).

Huperzia serrata Leaf Extract was included in Qualia Mind Caffeine Free 1.0 because it is a source of Huperzine A. The purpose of this ingredient was to support acetylcholine signaling. Qualia Mind Caffeine Free 1.0 included another ingredient that had a similar role, Celastrus paniculatus. In Qualia Mind Caffeine Free 2.0, we increased the amount of Celastrus and, importantly, we have our own new trademarked Celastrus paniculatus Seed Extract: SmartSeed™, developed for Qualia Life. Furthermore, three of our new ingredients have also been shown to support acetylcholine signaling: Polygala tenuifolia Root Extract, Terminalia chebula Fruit Extract (in Nutricog®), and Saffron Stigma Extract. With all of this additional support, we felt that Huperzia serrata Leaf extract was no longer needed in our formula.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® Caffeine Free contains no caffeine.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® Caffeine Free contains nootropics, adaptogens, brain tonic herbs, brain-essential nutrients, and vitamins. These ingredients support a number of brain structures and functions needed for alertness, focus, executive function, mood, memory, vision, and hearing. Their supportive benefits include healthy prefrontal cortex function, neurotransmission (e.g., acetylcholine, dopamine), neuroplasticity (e.g., BDNF), brain energy and bioenergetics (e.g., mitochondrial performance, ATP), cerebral blood flow, healthy brain cell membranes, neuroprotection, and antioxidant defenses. Qualia Mind Caffeine Free was also formulated with stress in mind, so several of the ingredients support a healthy stress response and resilience to stress.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

We encourage you to work with your physician to find an amount of capsules that you feel best supports the cognitive performance results you expect from a nootropic product.

Yes. We consider Qualia Mind® Caffeine Free to be compatible with intermittent fasting.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

The suggested serving size for Qualia Mind® Caffeine Free is 3-6 capsules a day.

Qualia Mind® Caffeine Free is intended for adults 18 years old and over. As always, we recommend consulting with your physician prior to use if you are pregnant or nursing, taking any medications or have any diagnosed medical conditions.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. If you want to take a few capsules of Qualia Mind® Caffeine Free with breakfast and a few more with lunch or dinner that would be fine.

Calories are not a standard part of labeling for most dietary supplements, because, unlike foods, or macronutrients (e.g., fats, carbohydrates, proteins), vitamins, minerals, amino acids, and herbs don’t have clearly defined calorie counts. While we don't have exact calorie data, we’d estimate that a six capsule serving size of Qualia Mind® Caffeine Free may have about 20-24 calories.

Qualia Mind® Caffeine Free was designed to be taken near the start of your day. But, since it has no caffeine, it can be taken in the middle of the day through dinner time if desired.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Take Qualia Mind® Caffeine Free in addition to Qualia Mitochondria+.

Women who are pregnant or nursing.

Children and teenagers under the age of 18.

Check with your doctor before taking Qualia Mind® Caffeine Free if…

• you are currently taking any prescription medications.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

Learning occurs, and fitness is built, through repetition and recovery. This principle applies to brain learning (it’s called spaced learning). It also applies to creating fitness, where most experts recommend taking 2-3 days each week to rest and recover from exercise. Living organisms are experts at adapting to things. By doing something intermittently, instead of every day, it counters the tendency for adaptation, which can be a useful way to approach things you plan on doing or taking for long periods of time.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Mind® Caffeine Free can be taken with Qualia Night®.

While there are no special instructions for getting started, we’ve found a good way to start is to take your dose of Qualia Mind® Caffeine Free about 1-2 hours after waking with a large glass of water.

Qualia Mind® Caffeine Free does not contain any ingredients reported to interact negatively with alcohol.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Mind® Caffeine Free can be taken with Qualia Resilience®.

Qualia Mind® Caffeine Free is a caffeine-free alternative to Qualia Mind: we have removed the caffeine-containing ingredients and replaced them with enXtra®, a clinically studied Alpinia galanga rhizome extract. The result is a caffeine-free formula that combines 30 carefully selected ingredients to support mental energy, alertness, attention, concentration, focus, memory, mood, motivation, vision, hearing, and overall cognitive performance.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Mind® Caffeine Free has an expiration date on the bottle, usually on the bottom of the bottle under the lot number. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025.

Yes. Qualia Mind® Caffeine Free can be taken with Qualia Probiotic+.

Qualia Mind® combines 32 ingredients that have been carefully selected to support mental energy, alertness, attention, concentration, focus, memory, mood, motivation, and overall cognitive performance. The word “thinking” can be used as a way to describe the brain’s primary function—taking in, processing, transmitting, and using information. The brain performs these functions using cognitive skills, which collectively allow us to perceive, reason, understand, learn, and remember. Related cognitive skills are grouped together into bigger cognitive domains including complex attention, executive functions, and memory. In the simplest sense, Qualia Mind was formulated to support an array of cognitive skills in these different domains.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Mind® was designed to complement Qualia Night®.

Yes. We consider Qualia Mind® to be compatible with intermittent fasting.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Yes. It’s perfectly fine to take fewer capsules than the suggested serving size. We encourage you to work with your physician to find an amount of capsules that you feel best supports the cognitive performance results you expect from a nootropic product.

The suggested serving size for Qualia Mind® is 3-6 capsules a day.

We do not recommend giving Qualia Mind® to children or teenagers, because (1) some of the ingredients have only been studied in adults, and (2) a 6 capsule suggested serving size contains 100 mg of caffeine, which when added to the amount of caffeine many teens consume in sodas, coffee drinks, energy drinks, etc., would place them above the amount recommended by doctors (The American Academy of Pediatrics suggests limiting caffeine intake to 100 mg in adolescents ages 12 to 18 years old and has not designated a safe threshold for caffeine in children 11 years old and younger).*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Most ingredients have many different forms of varying quality and potency. In every case, we chose the absolute highest grade form of each ingredient for Qualia.  

Additionally, the quantity of ingredients in Qualia vastly exceeds what is typical for nootropic products. Our raw ingredients cost is actually higher than the market cost of many of our competitors. We encourage you to research the ingredients in our product, the forms of those ingredients, the dosages, and then compare that information with other nootropics on the market. We think you will then agree that Qualia is at the top end in price because it is at the top end in quality.

Women who are pregnant or nursing.

Children and teenagers under the age of 18.

Check with your doctor before taking Qualia Mind® if…

• you are currently taking any prescription medications.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

If you notice something you think may be a side-effect, please stop taking Qualia Mind® and let us know by email or by calling or texting (855) 281-2328.

Research does not suggest any safety concern in taking Qualia Mind® and Qualia Focus® together, though we think of them as being “either/or” rather than “both together” products for most people. Part of the reason we think of them in this way is that each of these products was formulated to stand on its own as a nootropic. Another part of the reason is that each contains caffeine. And, the last part of the reason is that they have an overlap in several other ingredients (e.g., Celastrus, Ginkgo, L-theanine, some B-vitamins). Taking a full suggested serving size of Qualia Mind with Qualia Focus, as an example, would deliver 200 mg of caffeine, which is within the 50-200 mg range where caffeine performs exceptionally well as a nootropic. For people who are not sensitive to this amount of caffeine, we don’t believe that there is any reason why Qualia Mind and Qualia Focus can’t be used together.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Calories are not a standard part of labeling for most dietary supplements, because, unlike foods, or macronutrients (e.g., fats, carbohydrates, proteins), vitamins, minerals, amino acids, and herbs don’t have clearly defined calorie counts. While we don't have exact calorie data, we’d estimate that a six capsule serving size of Qualia Mind® may have about 20-24 calories.

Qualia Mind® has an expiration date on the bottle, usually on the bottom of the bottle under the lot number. Look for EXP and a number, such as EXP 04/2023, which means the expiration date for the bottle would be the end of April in 2023.

Yes. If you want to take several capsules of Qualia Mind® with breakfast and several more with lunch that would be fine. But, because Qualia Mind contains caffeine, we don’t recommend taking it with dinner. 

A 6 capsule serving size of Qualia Mind® contains 100 mg of caffeine. The nootropic range for caffeine for most people is in the range of 50-200 mg. To get the best overall nootropic experience from Qualia Mind, we recommend avoiding other products that contain caffeine in an amount that would, when combined with Qualia Mind, supply more than 200 mg of caffeine.

Qualia Mind® can be taken with or without food. However, some people prefer to take nootropic-containing products, such as Qualia Mind, away from food, because they feel like they notice the subjective response faster when it’s not combined with food.

We recommend storing Qualia Mind® in a cool dry place but not a refrigerator. Refrigeration promotes moisture condensation after a bottle has been opened, so is not recommended for storing the bottle—moisture is more of a problem for shelf-life in the ingredients in Qualia Mind than room temperature heat.

Yes. Qualia Mind® is vegan, gluten-free and non-GMO.

While there are no special instructions for getting started, we’ve found a good way to start is to take your dose of Qualia Mind® about 1-2 hours after waking with a large glass of water.

Everything Qualia is doing effects the chemistry on the brain side of the blood brain barrier.  

Qualia was designed for effecting whole body chemistry and very specifically the nervous system; both central and peripheral.  All the ingredients were chosen for their specific bioavailability to the pathways they were intended to affect. Whether that is through forms that directly cross the blood brain barrier or those that target the peripheral or central nervous system, the methodology here is to have all ingredients reach their intended targets via the different mechanisms affecting the whole body chemistry.

For more information on the ingredients and research behind Qualia please see QUALIA MIND: THE BUILDING OF A NOOTROPIC STACK

At this time, we do not offer samples of Qualia Mind®, however we do invite you to try the full version, with the assurance of our 100% in 100 Days Money Back Guarantee. There is no hassle. You do not have to return anything to us.  If you do not love it for any reason, simply get in touch via phone or email and let us know you’d like a refund.

Qualia Mind can be purchased on the Qualia Mind Shop page

The supplement industry is indeed the “Wild West” and there are a lot of snake oil salesmen out there with false claims and no ethical standards. Part of what inspired the creation of Qualia was in response to this exact problem.

Qualia is not a scam. We have a non-proprietary formulation - we publish exactly what’s in our product, with the exact amounts. We publish links to the research that support their safety and efficacy, which includes Phase II & III university and clinical trials, strong quantified self research data, and over 40+ years international research on nootropic stack formulation. We specifically designed our product with a set of ethical guidelines, so that we would avoid things like dependence or down regulation. In addition, the formulation was designed to produce long-term benefits to the brain, supporting the growth of new neurons, synaptic connections, neuroprotection, and so on.

For the full list of the ingredients in Qualia Mind, please review our formulation section. 

We invite you to read Qualia Mind Ingredients to better understand some of the thought processes behind the formulation and its ingredients.

Mind Instructions:

Mind Instructions:

Qualia Mind®’s intended effects are dose-dependent, varying with chemistry, body weight, general sensitivity and desired level of effect.  The suggested serving size is 3-6 capsules. We recommend taking Qualia Mind first thing in the morning, preferably on an empty stomach.* 

If stomach upset occurs, try it with breakfast instead. 

Everyone's chemistry is unique, of course, and some users find that taking an amount different than the suggested serving size  is key to optimizing the effects for their individual needs. If the suggested serving size does not match your needs, we encourage experimenting and adjusting the number of capsules you take with the help of your physician to find your optimal intake.* 

Cycling Your Use:

Qualia Mind is designed to be taken 5 days on and 2 days off each week.  This pattern has been shown to maximize the benefits while preventing desensitization. It does not matter if the “off-cycle” days are consecutive or apart, so long as they happen each week.*

For Best Effects:

Qualia Mind was designed to work for those getting adequate sleep, in generally good health, and practicing good self-care. Please read our full medical disclaimer on our website to make sure Qualia is right for you.  Good/adequate sleep is the number one issue preventing users from getting the desired effects from Qualia.  If you are not getting the results you were expecting, stop taking Qualia and work on getting enough sleep and try Qualia Mind again at a later date.  

Medical Disclaimer:

You should not take Qualia if you are on any SSRI or MAOI medication, nor is Qualia intended to treat or cure any medical condition. You should consult a physician prior to taking Qualia if you have any questions or concerns regarding Qualia as it relates to your unique medical history and prescribed medications. Please read our full medical disclaimer prior to use.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Learning occurs, and fitness is built, through repetition and recovery. This principle applies to brain learning (it’s called spaced learning). It also applies to creating fitness, where most experts recommend taking 2-3 days each week to rest and recover from exercise. Living organisms are experts at adapting to things. By doing something intermittently, instead of every day, it counters the tendency for adaptation, which is a useful way to approach things you plan on doing or taking for long periods of time. Our general preference is that, if something doesn’t need to be taken daily, it’s a good idea to build in breaks. We feel more strongly about building in weekly days off for dietary supplement products that contain caffeine and/or adaptogens, both of which are found in Qualia Mind®.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® was formulated for adults 18 years old and over. It is intended for people who want to experience nootropic benefits in areas including mental alertness, energy, attention, concentration, focus, motivation, productivity, mood, learning, and memory. Since most of us can benefit from an upgrade in one or more of these areas, the simplest answer is “almost all healthy adults.” Many of us have more than one demanding role. We are parents, partners, working professionals, athletes, students, and more. We work and play hard. To perform at our best, we can use premier cognitive support. We created Qualia Mind to support you in performing at your best.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Mind® was designed to be taken near the start of your day. This is true for most things with caffeine, since caffeine later in the day or at night may interfere with sleep.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

You don’t need to wait until you have your first food of the day to take Qualia Mind®. It’s fine to take Qualia Mind early in the day during your intermittent fasting window without food. It’s also okay to wait and take it when you eat your first food, as long as having caffeine at that time of the day does not interfere with your sleep.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Mind® was developed to support: (1) mental energy & alertness; (2) attention, focus & concentration; (3) motivation & productivity; (4) learning & memory; (5) the ability to expend more mental effort for longer periods of time; (6) and resilience to stress.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® contains 100 mg of caffeine in a 6 capsule serving size. Caffeine, especially when used prior to exercise, is very commonly dosed based on body weight in clinical studies. However, because the amount of caffeine contained in a 6-capsule dose would be in the range of what’s been used in studies even in persons with low body weights, we would not consider body weight to be particularly important for Qualia Mind. That said, it’s fine to choose to take fewer capsules of Qualia Mind for any reason, including if a person weighs less.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

The Dietary Guidelines for Americans cautions against mixing alcohol with caffeine. The reason for the caution is that when alcohol is mixed with caffeine, the caffeine can mask the effects of alcohol, making drinkers feel more alert than they would otherwise. The CDC's Alcohol and Caffeine Fact Sheet gives more information on their concerns. Since Qualia Mind® contains caffeine, we recommend it not be taken immediately before or at the same time as alcohol is consumed.

A six capsule serving size of Qualia Mind® contains 100 mg of caffeine (there’s about 17 mg of caffeine per capsule) from a combination of organic Coffeeberry® whole coffee fruit extract, guarana seed extract, and anhydrous caffeine. This 100 mg amount of caffeine is found in about an 8 ounce cup of coffee. We chose this amount of caffeine because caffeine’s nootropic (i.e., brain performance) range is generally from 50-200mg, while 100-600mg of caffeine are used for ergogenic (i.e., exercise/sports) purposes. So the amount of caffeine in Qualia Mind is in the lower part of the range most commonly used for mental and physical performance support purposes.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Mind® contains nootropics, adaptogens, brain tonic herbs, brain-essential nutrients, and vitamins. These ingredients have been shown to support a number of brain structures and functions needed for alertness, focus, executive function, mood, and memory. Their benefits include support for healthy prefrontal cortex function, neurotransmission (e.g., acetylcholine, dopamine), neuroplasticity (e.g., BDNF), brain energy and bioenergetics (e.g., mitochondrial performance, ATP), cerebral blood flow, healthy brain cell membranes, neuroprotection, and antioxidant defenses. Qualia Mind was also formulated with stress in mind, so several of the ingredients support a healthy stress response and resilience to stress.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Several ingredients in Qualia Mind®—Rhodiola, Ginkgo, PQQ, Lutein, Phosphatidylserine, and Nutricog®, as examples—can be thought of as more akin to the tortoise than the hare from Aesop’s fable (i.e., “slow and steady wins the race”). In other words, they support cognitive performance after steadily taking them for a sustained period of time. So, we recommend taking Qualia Mind for at least 2 months for best results. It’s also good to keep in mind that, in general, best responses to nootropics are expected when a person consistently gets sufficient sleep, adequate exercise, and eats a balanced diet.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

There are tens of thousands of different dietary supplements sold in the USA, with more added each year, so it is not possible for us to make any general recommendations about adding Qualia Mind® to an existing supplement regimen.

No, all of the ingredients in Qualia Mind® are not organic. The term “organic” refers to the way agricultural products are grown and processed. It is a term that has meaning for foods and beverages, but is not as meaningful for dietary supplements, because many ingredients including vitamins, minerals, amino acids, and many nootropic compounds are not agricultural products and cannot be certified as organic. 

We deeply care about the quality and safety of all Qualia products. Our ingredients are tested for purity, heavy metals, and microbial contamination. We also test the finished product to further ensure quality during manufacturing.

Qualia Mind is gluten-free, vegan, and non-GMO. It has no artificial colors, flavors, or sweeteners, and is also made with HPMC vegetarian capsules. Qualia Mind is not kosher.

Several ingredients in Qualia Mind®—caffeine and L-theanine, as examples—are fast-acting nootropics. In other words, they are routinely felt later the same day after taking a dose. In our pre-launch testing, alertness, energy, focus, and motivation were commonly experienced as soon as 30-60 minutes after taking a dose of Qualia Mind. Most participants experienced support in several nootropic areas related to energy, focus, motivation, productivity, and stress resilience during the first week of taking Qualia Mind.☨*

☨Proprietary consumer study of adults who took Qualia Mind.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Mind® was formulated to support hours of nootropic benefits and support mental energy throughout a busy day.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Nutricog is a clinically studied herbal blend made from Terminalia chebula and Boswellia serrata (Indian frankincense) extracts. It is marketed as a natural supplement designed to support cognitive health, including focus, memory, and overall mental performance.* You'll find it in Qualia Mind. 

Qualia Mind is available in two versions: the original formula, which contains about 90 mg of caffeine (roughly one cup of coffee), and Qualia Mind Caffeine Free. This allows users to choose based on their sensitivity or preference.

We recommend taking Qualia Mind for 5 days followed by 2 days off each week to maximize benefits and prevent habituation. Living organisms are experts at adapting to things. Taking 2 days off each week maximizes the benefits while preventing desensitization. It does not matter if the “off-cycle” days are consecutive or apart, so long as they happen each week. 

*For Qualia Mind® and Qualia Focus®*

This product contains chemicals that should not be taken by people on MAO inhibitors, SSRIs, or any other psychiatric medicines.

It should not be taken by people with psychiatric or neurological disorders, high blood pressure, heart conditions, endocrine disorders, cancer, phenylketonuria (PKU), or people on immunosuppressive therapy.

It should not be taken by pregnant or nursing mothers, or children under 18.

It should not be taken within a 24 hour time period from alcohol or recreational drugs.

If any undesired side effects are noticed, it should be discontinued immediately, and proper medical help sought if needed.

No claim is made of this product being used to treat, prevent, or cure any medical diagnosis or condition.

As with all dietary supplements, consult with your physician before taking any new supplements.

Please review our terms and conditions and privacy policy for additional information.

Qualia Mind® & Qualia Focus® are both fast-acting, research-backed nootropics designed to support a range of important cognitive skills, including alertness, motivation, attention (e.g., focus, concentration), and memory.* We believe that Qualia Focus delivers exceptional value and stands on its own as a great nootropic; however, it does not offer the premium nootropic experience of Qualia Mind. 

While Qualia Mind and Qualia Focus are designed to support some of the same cognitive areas, Qualia Mind was formulated to also support a wide range of additional cognitive skills, such as executive functions, emotional resilience, and skills within an area called social cognition. And, Qualia Mind was designed to offer more robust support for processes and functions involved with attention, accuracy, and focus in stressful environments and demanding situations, as well as support for hearing and vision.*

So, at a high level, Qualia Mind (1) is formulated to supply a much broader range of brain essential nutrition, (2) more holistically supports a wider range of cognitive skills, and (3) offers more robust support in areas involved in neuroplasticity, long-term brain health, and stress resilience. We believe Qualia Mind can do this because it has (1) a larger number of ingredients—Qualia Mind has 32 ingredients, while Qualia Focus has 14, (2) the suggested number of capsules to take is more (3-6 for Qualia Mind and only 2 for Qualia Focus), and (3) Qualia Mind’s higher price allowed us to include a combination of quite a few high cost ingredients that won’t be found together in nootropic doses in products at the Qualia Focus price point (such as Nutricog®, PQQ, Cognizin® Citicoline, Alpha-GPC, Phosphatidylserine, Lutemax Brain, and Rhodiola rosea).*

Because of the combination of capsule count and price, while both products have similar cores—the powerful nootropic pairing of theanine and caffeine, Celastrus paniculatus seed extract (the “intellect tree”), nootropic and adaptogen herbs for memory and stress support, and B-vitamins—there’s quite a bit of difference between the two products. This starts with what we use to supply caffeine, which is arguably the favorite ingredient among neurohackers for supporting alertness, energy, processing speed, reaction times, and motivation. Qualia Focus uses anhydrous caffeine (which is the most studied and commonly used type of caffeine among neurohackers and athletes), while Qualia Mind uses a blend of Organic Coffeeberry® Whole Coffee Fruit Extract, guarana seed extract, and anhydrous caffeine, because this blend also provides brain-supportive antioxidants and polyphenols. *

Both Qualia Mind and Focus include herbs and nootropics designed to support healthy functions like acetylcholine neurotransmission, neuroplasticity, and synaptogenesis, which are important for promoting cognitive skills such as focus, learning, and memory. But Qualia Mind offers far more support in these areas. It has the two nootropic forms of choline (e.g., Cognizin® Citicoline and Alpha-Glycerylphosphorylcholine [alpha-GPC]), and the clinically studied Nutricog® (Terminalia chebula fruit extract and Boswellia serrata gum resin extract) to offer more support for acetylcholine neurotransmission. Qualia Mind also contains more support for optimal synaptogenesis and neuroplasticity—these are critical functions for learning and memory—with the inclusion of ingredients such as Lion’s Mane mushroom and taurine.* 

While both Qualia Focus and Qualia Mind are formulated to support healthy dopamine signaling—critical for motivation and learning—Qualia Mind offers much more support, by including a dopamine precursor (N-Acetyl-L-Tyrosine) and dopamine signaling supportive botanical extracts including Saffron, Polygala tenuifolia Root, and Sabroxy® that are not included in Qualia Focus.*

We also designed Qualia Mind to be a go to product when it comes to supporting healthy brain aging. Because of this, Qualia Mind places more emphasis on a number of areas that are important to enhance long-term brain health, including mitochondrial support (which is why it has Pyrroloquinoline Quinone [PQQ] and Acetyl-L-Carnitine), nerve cell membrane fluidity and health (which is why Qualia Mind contains Phosphatidylserine, Lutein, and Zeaxanthin), and neuroprotection. It’s also an upgrade when it comes to stress support, with ingredients like Phosphatidylserine and Rhodiola rosea.* 

Which one should you buy? If you can afford it, Qualia Mind is our most comprehensive and premium product. If cost is an issue, Qualia Focus is a powerful product and we're delighted to be able to offer it as an option.

NOTE: Qualia Mind and Qualia Focus are not intended to stack together. 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

*For Qualia Mind and Qualia Mind Essentials

This product contains chemicals that should not be taken by people on MAO inhibitors, SSRIs, or any other psychiatric medicines.

It should not be taken by people with psychiatric or neurologic disorders, high blood pressure, heart conditions, endocrine disorders, cancer, phenylketonuria (PKU), or people on immunosuppressive therapy.

It should not be taken by pregnant or nursing mothers, or children under 18.

It should not be taken within a 24 hour time period from alcohol or recreational drugs.

If any undesired side effects are noticed, it should be discontinued immediately, and proper medical help sought if needed.

No claim is made of this product being used to treat or cure any medical diagnosis or condition.

As with all dietary supplements, consult with your physician before taking any new supplements.

Please review our terms and conditions and privacy policy for additional information.

Yes. Qualia Mind was designed to complement Qualia Vision.

Yes, for some Qualia products, and for others, on an everyday basis, it will depend on the person. We consider Qualia Mind® to be a great complement to other Qualia products such as Qualia Mitochondria+, Qualia Night®, Qualia Synbiotic®, Qualia Senolytic®, Qualia NAD+®, and Qualia Skin® (discontinued). Combining Qualia Mind with other Qualia nootropic products may be dependent on a person’s sensitivity to caffeine. 

Qualia Mind, Qualia Focus® (discontinued), and Qualia Energy Shot all contain caffeine, and caffeine is not a “more is better” nootropic ingredient. Combining Qualia Mind with either Qualia Focus, or Qualia Energy Shot would supply an amount of caffeine we’d consider to be at the top end of the nootropic range. 

This is an amount of caffeine that some people prefer but which may be too stimulating for other individuals. As always, we recommend that you consult with your physician when adding or combining supplements.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

We’re launching a new and improved Qualia Mind®! As we did with Qualia Life® 2.0, Qualia Mind 2.0 builds on and improves upon the original version while keeping the backbone of the formula the same. We’ve been keeping track of the feedback we receive from our community, the latest research, and new ingredients made available since we first launched Qualia Mind: we took this and more into account when we designed this upgrade.

Our goals for Qualia Mind 2.0 were ambitious. We wanted to make a great nootropic even better. We wanted to find out if we could succeed in doing this with fewer capsules. We wanted to add nutritional support for brain areas that were not as well supported with the original Qualia Mind, such as hearing and vision.* This required more than simply making slight changes to what’s in Qualia Mind; it was a more extensive reformulation. We added 13 new ingredients. To make room for them, 8 ingredients needed to be removed, and the amounts of several others changed, with some increasing and some decreasing.

We put the new formula to the test, comparing it to Qualia Mind 1.0. Qualia Mind 2.0 performed better.* We are proud of what we accomplished with Qualia Mind 1.0, but we’re even prouder of Qualia Mind 2.0. 

Here’s what’s changed and why.

We Have More Ingredients in Fewer Capsules 

One of our goals was to decrease the number of capsules in a serving of Qualia Mind without compromising quality. We know that taking so many capsules can be fatiguing for some people—it’s a comment we get a lot. But the fact is that what we see as the defining feature of Qualia Mind—a comprehensive support of neural pathways and processes that promote brain health and cognitive performance—is contingent on supplementing a high number of ingredients. To be able to target so many different aspects of brain function and performance, we need sufficient amounts of the ingredients that do so—and that inevitably means a relatively high capsule count.* Decreasing the number of capsules was not an easy task given our formulation approach, but we pulled it off!

In fact, in Qualia Mind 2.0, we managed to decrease the number of capsules per serving from 7 to 6, while also increasing the number of ingredients from 27 to 32. That means added benefits in fewer capsules!*

We Have More Trademarked Ingredients

The number of branded ingredients in Qualia Mind has increased from four in Mind 1.0 to eight in the new and improved Mind 2.0! 

Branded ingredients are ingredients that a supplier has gone to the effort and cost of trademarking. This is typically done to associate the brand name of the ingredient with claims of specific health benefits or higher quality. Often their development involved significantly more research and expense than non-trademarked (i.e., generic) ingredients. Because of the high R&D investment, branded ingredients are usually more expensive than generic ingredients. But the extra cost can be worth it because sometimes they are just that much better.* 

Having more trademarked ingredients is one of the ways the new Qualia Mind delivers even more value to you.*

We Included Up-and-Coming Nootropics

In the 6 plus years since Qualia Mind 1.0 launched, science has continued its march forward. There’s been new research. Some ingredients have appeared on the market that weren’t available before. Self-experimentation and N of 1 use has given insight into use of some nootropics and how they combine with other ingredients. Put simply, the nootropic community has not been static; we did not want Qualia Mind to be either. 

We consider ingredients like Nutricog® (a Terminalia chebula fruit extract and Boswellia serrata gum resin extract), Sabroxy® (Oroxylum indicum bark extract), and Polygala tenuifolia Root Extract as being rising stars in the nootropic community. We’re confident these ingredients will become more popular as more people learn about and experience them. You get to experience them today in Qualia Mind 2.0. 

We Brought Back Some Old Favorites

Before Qualia Mind, there was Qualia—the first nootropic formula we launched went by the name Qualia. It was supplied in two bottles, with instructions to take capsules from one of the bottles away from food first thing in the morning and capsules from the other bottle with breakfast (or food). This was a bit complicated for some people. This two-bottle formula was also a lot of capsules, with a full serving size of 11 capsules between both bottles.

To get from the 11 capsules in original Qualia to the 7 in Qualia Mind 1.0 required removing some ingredients. Lion’s Mane extract was one of these removals. Magnesium was another.  Both ingredients offer support for a healthy brain. Both are also among the nootropic communities favorites.* We’re excited to be able to offer both again as part of Qualia Mind 2.0.

We Included “Underappreciated” Nootropics

Nootropic ingredients can be thought of as some being underrated (they don’t get enough credit or appreciation), some being properly rated, and some being overrated. The overrated nootropics get used a lot; maybe more than they deserve. The underrated ones get overlooked. We wanted to correct this in Qualia Mind 2.0.

After reviewing an extensive amount of research and following what real world users experience, we think a strong and compelling argument can be made that Lutein and Zeaxanthin (supplied as Lutemax® Brain), Saffron, and Boron fall into the underrated category. They’ve been included in Qualia Mind 2.0. And, despite Celastrus paniculatus Seed Extract having been in Qualia Mind since it was first launched, we consider this as being another underrated and underappreciated nootropic—it’s on the very short list of our favorites. In Qualia Mind 2.0, we increased the amount of Celastrus by 50% (from 60 to 90 mg) and include it as SmartSeed™, an extract that is made specially for us.* 

We Added More Brain-Essential Nutrition*

Brain nutrients are compounds naturally found in the brain and used to support its structure and function. Qualia Mind 1.0 had 17 brain nutrients; Qualia Mind 2.0 has 21.* 

Qualia Mind 1.0 included most of the B complex vitamins, but Qualia Mind 2.0 supplies them all. So in addition to the B vitamins already found in Mind 1.0—Thiamine (as Thiamine HCl), Niacin (as Niacinamide), Pantothenic Acid (as Calcium Pantothenate), Vitamin B6 (as Pyridoxal 5'-Phosphate), and Vitamin B12 (as Methylcobalamin)—Mind 2.0 also includes Riboflavin, Biotin, and Folate (as L-5'-Methyltetrahydrofolate Calcium). Every B vitamin is either a cofactor or a precursor for a cofactor in a key metabolic process and all have essential roles in cellular metabolism, energy production, and brain health.* 

We also added two minerals involved in brain function to Qualia Mind 2.0: Magnesium (as Magnesium Aspartate) and Boron (as Boron Glycinate). Finally, we added the macular carotenoids Lutein and Zeaxanthin (from Lutemax® Brain), which are found in high amounts in the retina and the brain where they have antioxidant defense functions.*

We maintained the neurotransmitter precursors L-tyrosine (as N-Acetyl-L-Tyrosine, for dopamine support), Citicoline (as Cognizin®), Alpha-GPC (both for acetylcholine support); the membrane phospholipid Phosphatidylserine; the brain amino acid neuromodulator Taurine; the mitochondrial nutrients Pyrroloquinoline Quinone (PQQ) and Acetyl-L-Carnitine; and the antioxidant and neuroprotection-supporting vitamins Vitamin C (as Ascorbic Acid) and Vitamin D (as Cholecalciferol from VegD3®).*

We removed DL-Phenylalanine (an amino acid and dopamine precursor that had some redundancy with N-Acetyl-L-Tyrosine), Docosahexaenoic Acid (DHA, an omega-3 fatty acid found in membranes), and Uridine Monophosphate (a nucleotide that participates in the phosphatidylcholine synthesis pathway) (see why below) to make room for the new ingredients and as part of the solution to fewer capsules.*

We Added More Cognitive Support* 

Qualia Mind 2.0 provides upgraded support for several aspects of cognitive performance.* 

We upgraded memory support in Qualia Mind 2.0 by increasing the amount of Ginkgo biloba Leaf Extract from 50 mg to 120 mg. The increase to 120 mg matches an amount commonly used in clinical studies where Ginkgo has supported memory (and other aspects of cognition) in both older and younger adults. We also added Lutemax Brain Marigold Flower Extract, a source of the macular pigments Lutein and Zeaxanthin. These macular pigments, in general, and Lutemax specifically, have supported memory and markers of neuroplasticity in clinical studies. Furthermore, we added Nutricog®, a blend of Terminalia chebula Fruit Extract and Boswellia serrata Gum Resin Extract that supports memory as well as learning rate and capacity—this added support for learning is a new addition to Qualia Mind.* 

In addition to supporting cognitive performance, Ginkgo biloba also has adaptogenic actions—it supports healthy stress responses and a calm mood. Therefore, by increasing the amount of Ginkgo biloba, Qualia Mind 2.0 also upgrades its support of cognitive performance under stress. This upgrade was reinforced by adding Polygala tenuifolia Root Extract, another herb that supports healthy stress responses. Further contribution to this upgrade comes from also increasing the amount of Rhodiola rosea Root Extract, a well-known adaptogenic herb, from 300 mg in Qualia Mind 1.0 to 370 mg in Qualia Mind 2.0. This increase in the amount of Rhodiola rosea adds more support for mental energy and resistance to mental fatigue, further contributing to supporting the capacity for mental work under stress or fatiguing circumstances.*

We Added Support for Vision and Hearing

Vision and hearing are important for cognitive performance and maintaining cognitive health. Therefore, we wanted to include support for these key functions in Qualia Mind 2.0. 

One of the main factors contributing to the deterioration of visual health is oxidative stress in the retina. The  blue light emitted by screens is an example of an eye stressor. We added Lutein and Zeaxanthin (as Lutemax Brain Marigold Flower Extract) because these are antioxidant pigments that absorb excess blue light. These pigments accumulate in a central area of the retina called macula (which is why they’re called macular pigments or macular carotenoids). Lutein and Zeaxanthin must be obtained from the diet and adequate dietary levels are essential for a healthy visual response to blue light.

We also included Saffron Stigma Extract because it provides eye-healthy carotenoids and supports antioxidant defenses in the eye, retinal function and health, and visual acuity. Two ingredients that were already part of Qualia Mind 1.0 also support vision: Vitamin B12 as Methylcobalamin supports healthy nerve function and may help to support optic nerve health, which carries visual information to the brain; and Taurine is the most abundant amino acid in the retina, where it is essential for the light-capturing function of photoreceptors, acts as an antioxidant, and supports protection against stress from blue light and ultraviolet light.* 

Taurine is also found in the cochlea, the part of the inner ear involved in hearing, where it supports auditory neurons, neuroprotective functions in the cochlea, and auditory health. In Qualia Mind 2.0, we added magnesium as Magnesium Aspartate because it is a form that has been used in several clinical studies for supporting healthy hearing and resilience from noise stress. Pyrroloquinoline Quinone (PQQ) also offers support for hearing (read about vision and hearing support in Qualia Mind: The Building of a Nootropic Stack).*

We Created a Caffeine Stack

We increased the amount of caffeine from 90 mg to 100 mg. We made this increase because 100 mg of caffeine is an amount commonly used in studies of cognitive performance. This amount remains within the middle of the nootropic range, but you may feel a bit more support for alertness and processing speed. Most importantly, we switched from all of the caffeine coming from Coffeeberry® Whole Coffee Fruit Extract to a caffeine blend of Coffeeberry, Guarana Seed Extract, and Caffeine Anhydrous. The goal was to include a blend of caffeine sources that may be experienced slightly differently because of the other compounds each ingredient also provides. Caffeine anhydrous supplies just caffeine to provide the quick feeling of energy and alertness we expect from it. Extracts from whole coffee fruit (Coffeeberry®, i.e, not just the beans used to make coffee, but the whole coffee cherry that surrounds the bean) and guarana seeds supply caffeine and are also sources of health-promoting polyphenols.* 

What Was Removed and Why? 

Improving Qualia Mind meant adding new ingredients. These new ingredients were competing for the capsule space with existing ingredients. Improving the formula, while also decreasing the number of capsules, meant the competition was fierce. Put simply, some of the ingredients that were in Qualia Mind 1.0 were outcompeted. It doesn’t mean we don’t like these ingredients, but to add the upgrades we made, some ingredients needed to be subtracted. 

Docosahexaenoic Acid (DHA) was removed for a few reasons. DHA is responsible for a mild “fishy” smell in Qualia Mind 1.0 that many customers have commented on—removing DHA solves that issue. Similar to Qualia Mind 2.0, the competition for capsule space in Mind 1.0 was fierce. Because of this competition for capsule space, while we included DHA in the original Qualia Mind, we were only able to fit a modest amount in a serving. As a company, we strive to ensure that, when an ingredient is used in a formula, the amount is sufficient. The amount of DHA being included may not have been living up to this standard, so that was another reason that weighed into removing it. A third reason for removing DHA was because it is not an ingredient that would be expected to support short-term nootropic benefits—you often need to take it daily for a long time before cognitive effects are experienced. DHA was included in Qualia Mind 1.0 as an investment in long-term brain health. DHA is the most abundant omega-3 fatty acid in the brain, where it is a main structural component of the neuronal cell membrane and supports cell signaling functions. We concluded that we could maintain membrane structural support with our existing and new ingredients, many of which have antioxidant properties that support the protection of membranes against oxidative stress, one of the main threats to membrane health.* 

Uridine Monophosphate was included in Qualia Mind 1.0 in large part because of studies where it had been complementary with DHA. Its roles in the original formula were related to support for choline levels and brain membrane phospholipids. We decided to remove Uridine Monophosphate for a few reasons: First, Qualia Mind includes two ingredients that provide a more direct support of choline levels—Alpha-GPC and Citicoline as Cognizin®—so we felt we had that covered. Second, following ingestion, citicoline yields choline and cytidine, with some of the latter being converted into uridine in humans, so we still have some indirect uridine support in Qualia Mind 2.0. And finally, in preclinical studies, Uridine Monophosphate was often combined with DHA, and the combo was shown to support memory. So we felt that removing DHA could impact the benefits of Uridine Monophosphate. Furthermore, although Uridine Monophosphate is a nootropic ingredient appreciated among neurohackers, it is still poorly studied at the clinical level for cognitive support.* After weighing these factors, we felt that the capsule space taken up by Uridine Monophosphate could be better used by ingredients with stronger evidence of cognitive support (read about choline support in Qualia Mind: The Building of a Nootropic Stack).

DL-Phenylalanine, N-Acetyl-L-Tyrosine, and Mucuna Pruriens Seed Extract (a source of L-DOPA) were included in Qualia Mind 1.0 to support the dopamine synthesis pathway which progresses from L-Phenylalanine → L-Tyrosine → L-DOPA → Dopamine. Our goal was to provide all three precursors for full dopamine synthesis pathway support. For Qualia Mind 2.0, we decided to focus specifically on the rate-limiting step of the pathway, i.e., the step that determines the rate at which dopamine synthesis progresses: the conversion of L-tyrosine to L-DOPA by the enzyme tyrosine hydroxylase. Because this step can act as a bottleneck in the pathway, we figured that increasing the support for this step could be as beneficial as providing all the precursors (if not more beneficial!). Therefore, we removed DL-Phenylalanine and Mucuna Pruriens from the formula and maintained only the precursor used in the rate-limiting step: L-tyrosine (as N-Acetyl-L-Tyrosine); we also upgraded our support for the activity of the rate-limiting enzyme by increasing the amounts of two ingredients that support it—Rhodiola rosea Root Extract and Ginkgo biloba Leaf Extract—and adding another—Saffron Stigma Extract. And to further increase dopamine support in Qualia Mind 2.0, we added ingredients that promote the availability of dopamine in synapses and neurons by supporting balanced dopamine reuptake and breakdown (which Rhodiola and Saffron also support), including Oroxylum indicum bark extract (as Sabroxy®), Polygala tenuifolia Root Extract, and Terminalia chebula Fruit Extract (in Nutricog®) (read about dopamine support in Qualia Mind: The Building of a Nootropic Stack).*

Bacopa monnieri Extract, which was included in Qualia Mind 1.0 primarily to support cognitive function and mood, was replaced in Qualia Mind 2.0 with Nutricog®,  a blend of Terminalia chebula Fruit Extract and Boswellia serrata Gum Resin Extract. The clinical study with Nutricog® indicates that it may provide stronger benefits for memory and learning, support a wider range of cognitive areas, and provide noticeable cognitive support in a shorter time frame.*

One of the great benefits users of Bacopa often report is its adaptogenic properties and ability to foster a feeling of calm and thereby support cognition in contexts of stress. To ensure that Qualia Mind 2.0 not only maintains that benefit but actually upgrades it, we increased the amount of our main adaptogenic ingredient: Rhodiola rosea Root Extract. We also increased the amount of Ginkgo biloba Leaf Extract and added Polygala tenuifolia Root Extract and Terminalia chebula Fruit Extract (in Nutricog®), which have all been shown to support adaptogenic mechanisms.*

Artichoke Leaf Extract and Coleus forskohlii Root Extract were included in Qualia Mind 1.0 as a combo to support long-term potentiation (LTP, a neural mechanism of synaptic plasticity involved in learning and memory) by supporting cyclic adenosine monophosphate (cAMP), an intracellular signaling molecule (through Coleus) and phosphodiesterase-4 (PDE4), the enzyme that hydrolyzes cAMP (through Artichoke), as both molecules are involved in LTP. This benefit is only hypothetical and based on in vitro studies with each extract showing the referred mechanisms of action; there are no studies showing that their combination does indeed promote LTP. This does not mean it doesn’t, but because there’s no scientific evidence to support it, we decided to remove Artichoke and Coleus forskohlii and replace them with ingredients that have actually been shown to promote LTP in preclinical research: Saffron Stigma Extract, Polygala tenuifolia Root Extract, and Lion’s Mane Mushroom (as RealLionsMane™). Supporting LTP is a means to an end. The end, in this case, is optimal learning and memory.  We thought it made sense to focus more attention on the “end” rather than the means to the end, which led to an ingredient that has been shown to support learning and memory: Nutricog® (Terminalia chebula fruit extract and Boswellia serrata gum resin extract) (read about LTP support in Qualia Mind: The Building of a Nootropic Stack).

Huperzia serrata Leaf Extract was included in Qualia Mind 1.0 because it is a source of Huperzine A. The purpose of this ingredient was to support acetylcholine signaling. Qualia Mind 1.0 included another ingredient that had a similar role, Celastrus paniculatus. In Qualia Mind 2.0, we increased the amount of Celastrus and, importantly, we have our own new trademarked Celastrus paniculatus Seed Extract: SmartSeed™, developed for Qualia Life. Furthermore, three of our new ingredients have also been shown to support acetylcholine signaling: Polygala tenuifolia Root Extract, Terminalia chebula Fruit Extract (in Nutricog®), and Saffron Stigma Extract. With all of this additional support, we felt that Huperzia serrata Leaf extract was no longer needed in our formula.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

When we formulated the Qualia Nootropic Energy we assumed regular Qualia Mind users would want to occasionally have a Qualia Nootropic Energy. So we designed them to be able to be used together on the days when you want an extra boost. However, when it comes to daily use we think of these products as being more in the either/or category. In other words, for daily use we’d generally recommend either Qualia Nootropic Energy or Qualia Mind, but not both be used. 

Part of the reason we think of them in this way is that each of these products was formulated to stand on its own as a nootropic. Another part of the reason is that each contains caffeine. Taking a full dose of Qualia Mind with Qualia Nootropic Energy Shot would deliver 190 mg of caffeine, which is within the 50-200 mg range where caffeine performs. 

And the last part of the reason is that Qualia Nootropic Energy is formulated to provide some of the same cognitive support as what’s found in Qualia Mind (e.g., Celastrus paniculatus seed extract, L-theanine, alpha-GPC, n-acetyl-l-tyrosine, niacinamide).* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

When Qualia designed Qualia Mind, our goal was to support a range of what we think of as positive capacities. These are cognitive and emotional qualities that help us become better versions of ourselves in our professional and personal lives. A nootropic compound or formula can rob Peter to pay Paul, so to speak, boosting focus, as an example, but at the expense of patience. We get more done, but we also feel less calm or more irritable. 

When our team designed Qualia Mind, one of our goals was supporting calm energy and stress resilience. The experiences of calm energy feels very different than the edginess or irritability that can accompany energy drinks. It’s the attention, focus and drive to get things done, but in a more relaxed way. Resilience is the capacity to tolerate stress much better. When stress resilience goes up, the capacity to tap into positive cognitive and emotional qualities also goes up, while the tendency to get mired in more negative responses goes down. This goal was why we included ingredients that support calm energy and stress resilience. 

Bacopa monnieri is an example. It’s a nootropic Ayurvedic herb, supporting aspects of brain performance. But it does so in a way that also supports a healthier stress response.

Rhodiola rosea is an adaptogenic herb, which is the category of herbs that support adaptation to stress. Mental fatigue is one of the symptoms of higher stress: Rhodiola can help counter it. By helping us adapt to stress, some of the feelings that often accompany stress, such as anger and irritability can also be countered with Rhodiola.

When we look at ingredients, we are always thinking about whether they might be additive with other ingredients. It’s not only about single nutrients; it’s how nutrients interact together that is the key.

Ginkgo biloba is another nootropic herb. It tends to be mostly thought of as being supportive of longer term memory. When combined with Rhodiola, the combination supports better brain performance than either on its own, especially with working memory, sustained focus, and reaction times.

L-Theanine is found in green tea. It supports mental performance while also promoting less tension. It’s another example of how one ingredient can add to another. 

Caffeine has been one of the most studied compounds for brain performance. Its strengths, at least when taken in low-to-moderate amounts, are alertness, vigilance, attention, and reaction time. When caffeine is combined with L-theanine, the combination is better for focusing with speed and accuracy.

Yes. Qualia Mind® was designed to complement Qualia Mitochondria+.

Qualia Mind® is Qualia Life Sciences premium nootropic product. Put simply, it supports more brain structure and function processes (especially related to long-term brain health and performance) and was designed to be offer nootropic benefits that promote more cognitive skills and tasks—mental energy, alertness, attention, concentration, focus, memory, mood, motivation, and overall cognitive performance, stress resilience—than our other nootropic products. It is intended for people who want to experience the top of the line nootropic experience that Qualia Mind was formulated to deliver.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

How does Qualia Mitochondria+ work?

We’ve written a series of articles discussing how Qualia Mitochondria+ works in detail. But, in general, it works by helping our cells and mitochondria do more work, especially the types of tasks they tend to struggle to get to as we get older. When our cells and mitochondria can do more work, and get to all the important jobs we need them to do, we look, feel and function better.

Does Qualia Mitochondria+ work for everyone?

While it’s often implied that something will work for everybody, this does match the reality of complexity science or human individuality. A better assumption is to think in terms of response groupings. Exercise is a good example.

If we started a big group of people on the same exact exercise program, and followed how they respond over time, we’d find that some people got much more benefits than the overall group. These persons are called super-responders. Many people will have an average response. They’re responders. Some people will have either a less than average or no response (i.e., non-responders). And there’s likely to be a subset of persons who got injured. They were negative responders. This same type of grouping response reliably plays out when we test and iterate during our formulation process.

Response groups tend to follow a bell curve. One of our formulation goals is to shift the bell curve in a way that we end up with a high amount of super-responders (~33%) and an overall amount of super-responders and responders of about 80%. This leaves about 20% as non- and negative responders, with our goal being to have very few of this group being negative responders. Our testing of Qualia Mitochondria+ met this criteria. This product was not equal for everyone. About 1 out of 3 were super-responders. Almost half were responders. And, about 1 out of 5 were non-responders, with very few negative responders.

For someone who’s cells and mitochondria are already working at a high level, we wouldn’t expect them to notice as much as for someone whose cells and mitochondria are not. This is what we observed in our testing. In the subset of participants 35 and older, the percent of super-responders increased to about half, with almost all the rest being responders. So, in general, our testing to date has shown that persons in their mid-30’s and older seem to benefit more consistently and to higher amounts.

Qualia Mitochondria+ Disclaimer

When using dietary supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

When we first created Qualia Mitochondria+ (formerly Qualia Life), the company that supplies the patented form of Nicotinamide Riboside (NIAGEN®️) had decided they would not sell this ingredient to other companies.  

This changed recently, and we've now partnered with this supplier, offering NIAGEN®️ in our Qualia NAD+ formula. This formula takes the our complex systems science approach and applies it to making NAD+, in which NIAGEN®️ plays a very helpful role.

For people who wish to take Nicotinamide Riboside, Qualia NAD+ is a formula containing it. Qualia NAD+ also contains niacin (nicotinic acid), niacinamide (which are two additional NAD+ precursors), and 11 other cofactor ingredients that work together to support NAD+ production. 

Qualia Mitochondria+ also supplies excellent support for pathways and processes involved in metabolizing NAD+.* Qualia Mitochondria+ does not contain NMN (nicotinamide mononucleotide) because the FDA has determined that NMN is excluded from the definition of dietary supplement. 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Depending on health, age, and other factors, what you experience will vary. In the biohacker and quantified self communities, you’ll run across the acronym YMMV. This stands for “your mileage may vary.” It means that every person does not respond identically to the same thing. YMMV is seen with diet, exercise, sleep needs, and circadian preferences (i.e., some people are morning people; others are night people). It’s also seen with dietary supplements. Because of this, there’s a growing movement for what are called N-of-1 (or one person) experiments.

Not surprisingly, in our testing of Qualia Mitochondria+, we saw YMMV in action, when we look at the group as a whole (ranging in age from early 20’s to 70’s). Functional improvements individual people noticed varied. While most people noticed something, they did not all experience the same things.

About 6 out of 10 participants noticed higher energy and motivation levels. Close to the same number felt like they were better able to handle stress. Just over half felt a benefit in productivity … they were getting more meaningful work done than usual. For a few of them this was especially noticeable late in the day or in the evening, time periods when they would normally have exhausted their drive to be productive. Half of the group felt like the product allowed them to deal better with complex problems. About 4 out of 10 noticed a positive difference in their workouts. Almost one out of three people noticed an improvement in their sleep.

*Proprietary consumer study of 71 adults supplemented with 8 capsules a day, 5 days a week, for 3 weeks.

How soon will I notice something?

Qualia Mitochondria+ wasn’t designed to produce the type of immediate subjective response that our Qualia line of nootropics (Mind, Focus) are known for. Qualia Mitochondria+ is designed to give cells and mitochondria the nutritional support they need to work better. When they work better, we look, feel, and perform better … but this may take time.

Enhancing fundamental processes of cellular energy and mitochondrial performance is a slower process, because it gets to the roots of healthy aging, working from the ground up. In our testing, some people noticed some area of functional performance and/or subjective experience change almost immediately, many started to notice something within one week, but for most people it took a month of use.

It’s important to keep in mind that we don’t always feel a big difference as our cells and mitochondria slowly begin to perform better and produce more energy. Our senses are not as good at detecting slow, gradual enhancements as big, dramatic ones. It may be helpful to keep a journal of your experiences and how you are feeling over time so you can be more aware of those changes as they occur over time.

The Eternus Drink Mix retired in May 2021. The same formula in capsule format is available for sale in Qualia Mitochondria+. If you loved the drink mix format, you'll be happy to know we are researching new delivery technologies for future product releases.

Yes there is! All subscriptions receive 15% off. 

A good strategy, when starting anything new, is to start slow and gradually working your way up. This takes advantage of the body’s adaptive capacities and minimizes chances of poor response. Exercise is a great example of this. When starting a new exercise routine, the tendency is to want to do a lot right away. But this increases chances of having very sore muscles or getting injured. So, it’s better to start conservatively and slowly do more as your body gets accustomed to the new routine.

This same principle, starting low and adding more gradually, can be applied to taking dietary supplements. Starting by doing less is done by taking 1-2 capsules a day for the first few days (three days is a good rule of thumb). Then gradually add 1-2 more capsules every few days till you reach the full dose. This gradual approach can be especially important for people who are: already taking a lot of other supplements, or tend to be more sensitive to dietary supplements or foods.

In general, we recommend taking the full dose. The full dose provides the studied amounts of many of the ingredients (this is an important part of being able to make accurate structure/function claims) and is the dose we designed the formulation to deliver and have studied in our testing.

Feel free to adjust the dose as needed, whether this is over time or because of sensitivity to dietary supplements, in general, or to this formulation. Because of biochemical individuality and many other factors, we don’t all respond the same way to the same ingredients or doses. We don’t all have the same objectives or goals in mind. So, it’s perfectly fine to experiment with taking a lower dose that works best for you and your chemistry.

For some, it may be a good idea to begin slowly as you get started with this product. Starting by doing less is done by taking 1-2 capsules a day for the first few days (three days is a good rule of thumb). Then gradually add 1-2 more capsules every few days till you reach the full dose. This gradual approach can be especially important for people who are already taking a lot of other supplements, or tend to be more sensitive to dietary supplements or foods.

Yes you can stack Qualia Mitochondria+ with other Qualia formulations. 

When we designed Qualia Mitochondria+, we did so understanding people would take it with one of the other Qualia products. Because of this, we made sure that the formulations, when combined, wouldn’t be giving too much of any individual nutrient. We are not a “more is better” company when it comes to the formulation of our products. It was very important to us to make sure the amounts of every ingredient would stay within a safe range when this product was taken with Qualia.

While we’ve found that people often respond to Qualia Mind better when it’s taken without food, there’s a lot more flexibility on when you take Qualia Mitochondria+. The important thing is finding a routine that that works best for you.

Qualia Mitochondria+ (formerly Qualia Life) contains a blend of vitamins, minerals, herbal extracts, and other compounds designed to support cellular energy and healthy aging. Key ingredients include Vitamin K2 (as Vitaquinone® MK-7), Vitamin B2 (Riboflavin), Biotin, Niacinamide (Vitamin B3), Vitamin B1 (Thiamine), and Vitamin B5 (Calcium Pantothenate). The full formula also includes additional nutrients, antioxidants, adaptogens, and mitochondrial support compounds such as CoQ10, PQQ, resveratrol, quercetin, and acetyl-L-carnitine.

For the full list of the ingredients in Qualia Mitochondria+, why they were chosen, and the research behind them, please review our formulation section.

Qualia Mitochondria+ can be taken by any adults, but the groups we had in mind when we formulated and tested it include:

• Middle-age people who want to promote healthy aging.
• Older people wanting to feel more alive and experience more healthy years.
• Adults with chronic stress who want to do more to help their body better respond better.
• Persons with interest in supporting metabolic function and/or promoting better shape.
• Anyone with a big interest in healthy aging and supporting the fundamental mechanisms related to aging gracefully.

In our testing, we have seen more noticeable positive functional and performance enhancements in persons who were 35 and older than in younger adults. This makes sense because cellular and mitochondrial function need more support as we age.

For a deep dive into the design behind Qualia Mitochondria+, please review Qualia Mitochondria+: Putting the Healthy Aging Puzzle Together

How much water should I drink with Qualia Mitochondria+.?

We recommend drinking Qualia Mitochondria+ with water and drinking plenty of fluids throughout the day, especially during the first week. One of the ingredients—creatine (as tricreatine malate)—is believed to pull water into cells. Because of this, it’s important to stay hydrated while taking Qualia Mitochondria+..

Should I take Qualia Mitochondria+ with or without food?

In general, we recommend taking Qualia Life with food. Some of the ingredients are fat-soluble, so taking them with food, especially if it contains at least a small amount of fat or oil, would be expected to help with absorption. It’s fine to take it a bit before eating the food (or drinking a smoothie), in the middle, or a bit after eating. Digestion doesn’t happen all at once.

Is it OK to take Qualia Mitochondria+ in a fasted state?

We've had lots of people take Qualia Mitochondria+ in the morning without food. Only a few of the ingredients are fat-soluble (CoQ10 and Vitamin K2) and would be expected to be better absorbed with fat, but most of the ingredients won't be impacted. If you are drinking Bulletproof coffee in the morning, taking Qualia Mitochondria+ with or soon after that would give you plenty of fat for better absorbing the CoQ10 as an example. And, we'd consider it completely fine to take earlier in the day without food if that's more convenient for you.

What time of day Is best to take Qualia Mitochondria+?

We recommend taking Qualia Mitochondria+ in the morning as opposed to dinner because things taken at dinner, in our experience, have a much more individual impact on sleep, while taking them in the morning seems to be more forgiving and they don't disrupt sleep (sleep quality has improved for quite a few people taking Qualia Mitochondria+ in the morning or lunch but we haven't studied this for dinner dosing). 

Qualia Mitochondria+ was designed to make your cells and mitochondria (the powerhouses of cells) work better. When your cells and mitochondria are able to do their jobs better, we look, feel, and perform better.

Qualia Mitochondria+ was formulated to comprehensively support the multiple interacting metabolic pathways, signaling processes, and cellular mechanisms of long-term healthy function. Better cells and mitochondrial function translates into more high-performing days and longer healthy years.

Qualia was designed to support the integrity of the natural pathways that mediate cognitive and performative functions, leaving a healthier, more balanced regulatory system even after discontinuing use. So while some of the ingredients give you immediate benefits or benefits for a few days, other ingredients are busy actually building more neurons and synapses, repairing cell walls, etc. The result is that if you use Qualia for months, you should benefit from a system upgrade – not just an enhancement.

If you notice something you think may be a side-effect, please stop taking Qualia Mitochondria+ and let us know by email or by calling or texting (855) 281-2328.

Qualia Mitochondria+ was designed to make your cells and mitochondria (the powerhouses of cells) work better. When your cells and mitochondria are able to do their jobs better, we look, feel, and perform better.

Qualia Mitochondria+ was formulated to comprehensively support the multiple interacting metabolic pathways, signaling processes, and cellular mechanisms of long-term healthy function. Better cells and mitochondrial function translates into more high-performing days and longer healthy years.

Qualia uses a model of science called complex systems science. One of the core principles is adaptation. Living organisms are experts at adapting to things. 

Exercise is an excellent example of this. When we start a new exercise program muscles, and other systems like the heart and lungs, adapt to it which allows us to perform better. To optimize our response to exercise, we need to perform it and also allow enough time to recover from it. Because of this, a good trainer or coach wouldn’t have a person do the same exercise every day (i.e., continuous exercise); they’d have them take days off (i.e., intermittent exercise). 

By doing something intermittently, instead of continuously, we typically get more benefits and we continue to get benefits over long periods of time. Intermittent fasting is another example. During the fast, the body gets rid of some dysfunctional parts of cells and mitochondria. After the fast, during refeeding, it builds new better ones. Both the fasting and refeeding play a role. Unless there’s something a person needs to do or take everyday we think it’s a good general strategy to take breaks from it.

We've had lots of people take Qualia Mitochondria+ in the morning without food. Only a few of the ingredients are fat-soluble (CoQ10 and Vitamin K2) and would be expected to be better absorbed with fat, but most of the ingredients won't be impacted. If you are drinking Bulletproof coffee in the morning, taking Qualia Mitochondria+ with or soon after that would give you plenty of fat for better absorbing the CoQ10 as an example. 

Wondering what the sugar content of Qualia Life sachets are? And if you can take it with a Keto diet?

Qualia Life Drink Packets use a blend of D-Ribose (5 grams) and Monk Fruit Extract (120 mg). Monk fruit is considered to be a Keto friendly sweetener, because it has no carbohydrates (see https://perfectketo.com/monk-fruit/). While D-ribose is classified as a carbohydrate, it is metabolized very differently from sugars and simple carbohydrates. In the only study we've seen, a 30 gram infusion of D-ribose did not change ketones after an overnight fast. More research (including oral dosing) is needed before we'd be confident it's Keto friendly. Once you figure out the best way to integrate the Qualia Life Drink Packets into your Keto lifestyle, please let us know what you are finding.

Qualia Mitochondria+ Capsule Instructions:

Qualia Mitochondria+ effects are dose-dependent, varying with body weight, general sensitivity and desired level of effect. 

The standard dose for most people is 8 capsules. Take Qualia Mitochondria+ first thing in the morning, with food. 

Everyone's chemistry is unique, of course, and some users find that increasing or decreasing the standard dosage is key to optimizing the effects for their individual needs. If the standard dosage does not match your needs, we encourage experimenting and adjusting your dosage in order to find your optimal intake.  

Cycling Your Use:

Qualia Mitochondria+ is designed to be taken 5 days on and 2 days off each week.  This maximizes the benefits while preventing desensitization. It does not matter if the “off-cycle” days are consecutive or apart, so long as they happen each week.

For Best Effects:

Qualia Mitochondria+ was designed to work for those getting adequate sleep, in generally good health, and practicing good self-care.  

Medical Disclaimer:

This product should not be taken by pregnant or nursing mothers, or children under 18.

This product should not be taken within 12 hours of bedtime as it may cause restlessness. If any undesired side effects are noticed, discontinue product immediately, and seek proper medical attention if needed.

Before taking Qualia Mitochondria+ or any supplement please consult with your physician beforehand to confirm that there are no potential contraindications.

The short answer is that this helps prevent the tendency to adapt or habituate. Living organisms are experts at adapting to things. Exercise is an excellent example of this. When we start a new exercise program muscles, and other systems like the heart and lungs, adapt to it, which allows us to perform better. To optimize our response to exercise, we need to perform it, and allow time to recover from it. By doing something intermittently, instead of continuously, we typically get more benefits and continue to get benefits over long periods of time.

We recommend that Qualia Night be taken several hours before bedtime, and that is not an ideal time to take melatonin for most people. Like many processes in the body, both the what, in this case melatonin, and the when, it’s timing, are important. Secretion of melatonin peaks in the middle of the night. The timing of this surge in melatonin synchronizes physiological cycles of the body. Because melatonin levels increase quickly after taking it orally, you’ll usually see recommendations to take it shortly before going to bed. When taken near a person’s normal bedtime, the increase in melatonin produced by the supplement will be close to the time melatonin is going to surge anyway. If taken a few hours before bedtime, the increase in melatonin will be earlier. For many people that would shift the time they’d naturally fall asleep and wake up to be earlier. And while they were adjusting to the new timing, in a sense, the melatonin would be causing something akin to jetlag, abruptly shifting the body’s circadian rhythms. Those are not things we wanted to do. So instead of including melatonin, Qualia Night contains ingredients the brain can use to make melatonin when it needs it. For more on the mechanisms supported and the approach we took to build the product see: QUALIA NIGHT - THE BUILDING OF A COMPREHENSIVE SLEEP SUPPORT STACK

Qualia Night is a dietary supplement designed to support the brain and body in shifting  gears from our active daytime physiology into what’s needed to relax, support healthy sleep, and wake feeling refreshed. It is a blend of 25 carefully selected ingredients that can help give you support to get quality sleep and more productive daytimes.

The simplest answer is “any adult who would benefit from getting sounder sleep and feeling more energized, alert, and focused the next day.” That said, Qualia Night was specifically designed for people:

• Who might have trouble de-stressing or winding down after work; 

• Who want to be productive during the night hours but with a sense of calm energy / unhurriedness;

• Who are interested in supporting long-term brain performance;

• Who want to slowly enhance sleep quality without taking herbs/supplements that are designed to produce a feeling of sleepiness shortly after taking them.

Women who are pregnant or nursing.

Children and teens.

Check with your doctor before taking Qualia Night if…

• You are currently taking any prescription medications.

• You have a medical condition that makes you concerned about taking it.

• You are concerned about taking it for any reason.

Qualia Night was designed first and foremost to help users perform better during their days by helping with nightly relaxation and rejuvenation. A key point is that what happens at night will have a dramatic effect on how we perform the next day. Users frequently comment on what would be considered nootropic benefits, which increase over time. In other words, one thing you should expect would be feelings of enhanced mood, energy, focus, motivation, and productivity ... all of which tend to be felt more after several weeks than after several days. Qualia Night was also designed to broadly support many areas of sleep quality. These include helping with feeling more calm and relaxed at night (i.e., readiness for sleep), ease of falling or staying asleep, soundness of sleep and vividness of dreams, and waking feeling more refreshed and ready for the next day.

Most users notice one or more of the following within the first two weeks of taking Qualia Night: (1) feeling more relaxed at night, (2) experiencing sounder sleep, (3) waking more refreshed and energized, and (4) having more productive days. While Qualia Night was designed to work over time, it’s not uncommon to experience some of these within a few days of starting Qualia NIght.

There are many dietary supplements available which claim to help people sleep. They typically use herbs intended to produce sleepiness, high doses of melatonin, or both. Unfortunately, these approaches don’t comprehensively address everything needed to produce high quality sleep. Qualia Night is designed to support the important pathways required for quality sleep and the processes that allow for cellular rejuvenation. Some of the reasons that we have difficulty with relaxing at night and getting quality sleep have to do with brain energy production, sleep homeostasis mechanisms, pineal gland melatonin production, the brain’s main inhibitory neurotransmitter GABA, gut-brain axis performance, brain growth & regenerative factors, and stress. Qualia Night was designed to support all of these areas. It does this without relying on botanical sedatives or giving melatonin. Instead, it is designed to help the brain better self-regulate, making more of what would help it at night and less of what won’t.

Our general recommendation is to take Qualia Night with food because some of the ingredients are fat-soluble. This means they would be expected to be more bioavailable if consumed with or near a meal or snack that contains some fat. But, it is fine to take it without food if you forget to take it with dinner or if that is not convenient for your schedule. 

Before bedtime sleep supplements typically use herbs, melatonin, or both to induce a feeling of drowsiness. Qualia Night is not designed as this type of sleep supplement. Instead, it’s designed to help the body shift into the relaxation and rejuvenation modes needed to get sounder sleep and better next day performance … over time. While it may help with sleep in a single night, it was not what it was designed for.

Qualia Night combines 25 carefully selected ingredients. These ingredients were selected for several reasons. Some ingredients support the brain in making and responding to major sleep regulating neurotransmitters (such as GABA), neurohormones (melatonin), and sleep homeostasis drivers (like adenosine and uridine). One of the reasons many people have difficulty getting good sleep has to do with brain mitochondrial performance, so we included several polyphenol-rich food extracts, including olive fruit, blueberry, grape, sesame, and saffron to better support the brain in making energy. Stress, and tension contribute to an inability to relax at night so we included adaptogens and other ingredients that support relaxation and resilience to stress. In a general sense, the body has daytime functions and night time functions. At night, cleanup, restoration and rejuvenation dominate. So we included ingredients that support stem cell processes, brain growth and healing, and antioxidant defenses. 

No. It’s fine to take a lower dose. A small subset of users prefer taking only 1 to 2 capsules. While 4 capsules is the recommended dose, and is the most common way users take Qualia Night, it is fine to adjust the dose lower as needed to find what works best for you and your chemistry.

Qualia Night will work best when you also pay attention to several diet and lifestyle habits. Evening body clock functions perform the best when the body can predict when to schedule major jobs. This predictability is dictated by the timing of two behaviors that are major time giving cues, called zeitgebers, for the body clock—sleep-wake cycles and meal timing. Because of their role in time-keeping, we recommend going to bed at about the same time most nights and eating dinner on a regular schedule. It’s also important to limit behaviors that act as dyschronogens (i.e., things that disrupt body clock timing). The four things that tend to be the most important for most people are to: (1) limit caffeine to early in the day (ideally prior to noon), (2) if you drink alcohol, do so in moderation and ideally at or near dinner time, (3) allow at least a few hours between eating dinner and bedtime, and (4) if you are using a screen (e.g., TV, computer, smartphone) after dark, consider wearing blue-blocking glasses Comment end.

Our general recommendation is to take Qualia Night several hours before bedtime, but this is not a hard rule. A small subset of users have found that Qualia Night has worked better for them when taking it closer to going to bed. So it is fine to adjust the timing as needed to find what works best for you.

Yes! When we designed Qualia Night, we did so assuming people would take it with our other Qualia products. Because of this, we made sure that the products, when combined, wouldn’t be giving too much of any individual nutrient. We are not a “more is better” company when it comes to the formulation of our products. It was very important for us to make sure the amount of every ingredient would stay within a safe range when this product was taken with any Qualia product.

We don't have exact calorie data on any of our formulations. Calories are not a standard part of labeling for dietary supplements, because, unlike foods, or macronutrients (e.g., fats, carbohydrates, proteins), vitamins, minerals, amino acids, and herbs don’t have clearly defined calorie counts.

Can I take Qualia Night while intermittent fasting?

Yes. We consider Qualia Night to be compatible with intermittent fasting.

The intermittent fasting window I follow means that the last food I eat is more than several hours before going to bed. What should I do?

It’s fine to take Qualia Night earlier so that the timing matches when you’d be eating your last food before going to bed that night.

Qualia Night does not contain any ingredients reported to interact negatively with alcohol. But, in general, alcohol interferes with getting high quality sleep, so we don't recommend having more than 1 or 2 drinks in order to get the most benefits from taking Qualia Night.

Take up to 4 capsules at dinner or several hours before bedtime. This product is non-sedating and designed to be taken earlier in the evening (unlike before bedtime sleep aids). Qualia Night is designed to be taken 5 days on and 2 days off each week. It does not matter if the "off-cycle" days are consecutive or apart, so long as they happen each week.

Can I take Qualia Night in addition to Qualia Life?  

Yes. Qualia Night was designed to be able to be taken with Qualia Life.

Can I take Qualia Night in addition to Qualia Mind or Focus?  

Yes. Qualia Night was designed to be able to be taken with Qualia Mind or with Qualia Mind Essentials.

Can I take Qualia Night in addition to Qualia Nootropic Energy Shot?  

Yes. Qualia Night was designed to be able to be taken with Qualia Nootropic Energy Shot.

Qualia Senolytic is intended to be a great complement to other Qualia products, especially the first product we created in our longevity line, Qualia Mitochondria+. To get the most out of Qualia Mitochondria+ we recommend that you take Qualia Mitochondria+ throughout the month.

Behaviors and strategies that support immune system performance would be expected to also complement senolytics.* We recommend focusing on: (1) Consistently getting enough quality sleep—sleep is a major determinant of how well the immune system performs; (2) Regularly exercising in ways that create fitness—being sedentary and excessive exercise can both weaken immune performance (think Goldilocks principle when it comes to exercise); (3) Managing stress—higher stress is hard on the immune system; and (4) Practicing some type of fasting behavior for several days every three months or so—Valter Longo’s (interviewed on Collective Insight Podcast) fasting-mimicking diet is an example of one of these approaches; it helps rejuvenate immune cells*. And, of course, eating a healthy diet is important for immune system health and complements senolytic supplement protocols.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

The aspects of healthy function that Qualia Senolytic may influence can vary person-to-person: for some people it may be the skin, for other people it may be fat or muscle tissue, for others it could be the brain, joints, immune system, etc. Because of this, there is no one way that Qualia Senolytic is experienced.* With the above in mind, the areas you should expect benefits are the areas that are typically most impacted during aging, so pay attention to signs of healthier skin, muscles, joints and brain functions, as well as overall health and energy, after two-to-three months of taking Qualia Senolytic.* 

 Some of the potential side effects of taking Qualia Senolytic include light headaches, lack of energy, slight irritability, gastrointestinal disturbances, and other mildly unpleasant symptoms. To mitigate these effects, we recommend eating food and drinking extra water during the two-day Senolytic treatment period.

These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

We recommend taking all 6 capsules of Qualia Senolytic one day, and the following day, take the other 6 capsules. It doesn't matter if you take them all at once or spread throughout the day.

Our general recommendation is to take Qualia Senolytic with food. The reason for this recommendation is because (1) with food is the most common way senolytics have been used in studies, and (2) Qualia Senolytic contains concentrated food extracts, some of which may be more bioavailable if taken with food.

We would also recommend drinking some extra water during the two day treatment.

Qualia Senolytic is also intended to be a great complement to other Qualia products, especially the first product we created in our Longevity line, Qualia Mitochondria+.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Our general recommendation is to take Qualia Senolytic with food. 

The reason for this recommendation is because (1) with food is the most common way senolytic supplements have been used in studies, and (2) Qualia Senolytic contains concentrated food extracts, some of which may be more bioavailable if taken with food.* 

When we tested Qualia Senolytic prior to launch, some participants chose to take it with food and others took it without food. 

So, if taking supplements on an empty stomach is something that you tolerate well and find more convenient, feel free to take it without food.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Intermittent use—some experts call this a “hit and run” approach—is the way senolytic supplements are most commonly used to support healthy aging.* The “hit and run” approach means that senolytics are recommended to be taken for a couple of days followed by a longer period of time when they are not taken. 

Senescent cells are created in, and removed from tissues constantly throughout life (and over shorter periods of time like a month). The goal of taking senolytics is to shift the balance in favor of removal, which should not require daily dosing since senescent cells accumulate slowly.* 

Think about this “hit and run” dosing as being a bit like how you might approach pruning a plant: pruning is something you’d want to do frequently but not every day. Another way to think about taking senolytics is as being akin to a water fast or detox protocol, which are not something done every day, but instead, would be something done for a few days periodically to support health goals.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic should be thought of as a product that pays healthy aging dividends over time and with repeated cycles of use. 

In the pilot study we did of Qualia Senolytic prior to bringing it to market, the participants were between the ages of 32 and 66 and had at least a moderate degree of difficulty in comfortably performing a variety of activities of daily living (this is something that frequently accompanies aging). 

Most of the participants reported greater ease in comfortably performing these activities and less of the occasional stiffness that can accompany aging after two dosing cycles of Qualia Senolytic (i.e., after taking a full dose of Qualia Senolytic for 2 days, taking a few weeks off, and then taking another full dose of Qualia Senolytic for 2 days).* 

While this is one use case, we created a senolytic supplement like Qualia Senolytic to support healthy aging in many areas (brain, muscles, immunity, joint, skin, etc.) so benefits may show up at varying speeds and in a variety of areas of function in different people depending on where aging is taking a toll.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. While our general recommendation is to take 6 capsules a day on the 2 days a month we recommend that you take Qualia Senolytic, it’s perfectly fine to take a lower dose. But the trade-off of taking a lower dose is getting less senolytic support, which may be just right for a younger, lighter weight, or very healthy adult, but may be sub-optimal support for an older, heavier, or less healthy person, as an example.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease

By our late 20’s, most of us will begin noticing changes caused by getting older. By our 40’s, we’ve gone beyond noticing …many of us are feeling aspects of the aging process. 

Some scientists believe that one of the reasons we notice and feel some aspects of (unhealthy) aging is because of stressed or worn out cells called senescent cells. 

Qualia Senolytic was formulated to support tissues in pruning away these senescent cells. Because senescent cells tend to gradually accumulate with the passing of years, senolytic supplements like Qualia Senolytic was created for adults in their 40’s and older or younger adults who may already be noticing or feeling the aging process.* 

Qualia Senolytic can also be taken periodically to support adults of all ages in managing senescent cells (AKA zombie cells) as a way to proactively promote healthy aging.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic is designed to support healthy aging by targeting and clearing senescent cells—damaged cells that no longer function properly but remain in the body. Benefits may include increased energy, reduced feelings of fatigue, support for tissue repair, and overall rejuvenation. By helping remove these “stagnant” cells, it aims to promote vitality, mobility, and healthier cellular function.*

Foods rich in natural senolytics—compounds that help clear out senescent or “zombie” cells—include those high in fisetin, quercetin, and resveratrol. Examples are berries (like strawberries and blueberries), apples, cruciferous vegetables (such as broccoli and kale), leafy greens, dark chocolate, fatty fish, and plant-based sources like green tea, turmeric, ginger, and long pepper.

However, although there are many different fruits, vegetables, herbs, spices, and other types of foods in the diet that contain senolytic or senomorphic compounds, no food source has been shown to contain senolytics in sufficient amounts for actual senolytic benefits, so far. In other words, in research studies, these compounds showed senolytic action (i.e., they were able to promote the death of senescent cells) only at amounts that are much higher than those available in foods. 

We do not recommend taking Qualia Senolytic every day. Intermittent use—some experts call this a “hit and run” approach—is the way senolytics are most commonly used in clinical studies to support healthy aging. It is also the way we have supplemented Qualia Senolytic in our 3 studies.*

Quercefit® is a patented form of quercetin, a natural antioxidant found in plants like Sophora japonica L. It uses phytosome technology, where quercetin is bound to phospholipids, improving its absorption and bioavailability in the body compared to standard quercetin supplements. You'll find it in Qualia Senolytic. 

The most potent natural senolytic identified so far is fisetin, a flavonoid found in fruits like strawberries, apples, and persimmons. Research shows that fisetin effectively clears senescent cells in animal studies, reducing markers of aging across multiple tissues through a “hit-and-run” mechanism. There are several ongoing clinical studies sponsored by the Mayo Clinic to assess the senolytic action of fisetin in humans.*

Yes. If you want to take part of the Qualia Senolytic with one meal (such as breakfast) and part with another meal (like lunch or dinner) or spread equally between three meals on the days you take it, that would be fine.

Yes. While our general recommendation is to take 6 capsules a day on the 2 days a month we recommend that you take Qualia Senolytic, it’s perfectly fine to take a lower dose. But the trade-off of taking a lower dose is getting less senolytic support, which may be just right for a younger, lighter weight, or very healthy adult, but may be sub-optimal support for an older, heavier, or less healthy person, as an example.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic contains a combination of nine vegan ingredients and was formulated to be taken on two consecutive days once a month. It was created to support healthy aging in an area called “cellular senescence.”* But what is that?

Aspects of cellular structure and function gradually shift in certain predictable ways as a normal part of the aging process. Scientists refer to nine of these gradual shifts as the Hallmarks of Aging—think of a hallmark in this case as meaning a distinguishing characteristic. Cellular senescence is one of the nine characteristics; it has to do with a special type of stressed or worn out cell called a senescent cell.

Senescent cells are created and removed from tissues constantly throughout life. They are formed as a routine part of normal healthy function. Muscle tissues, as an example, create senescent cells after intense exercise as part of recovery.

Senescent cells are also formed when a cell becomes so stressed or worn out that it’s not worth putting in cellular work to maintain or repair it (replacing it would be a better use of cellular resources).

As we get older, healthy creation and removal functions tend to shift in ways that result in gradual increases in the proportion of senescent cells in some, often many different tissues—removal functions fall behind. This occurs for two main reasons.

Senescent cells should proceed through a series of molecular steps in a biological process that got its name from the Greek word for “falling off,” in the sense of ripe fruit falling from trees, leaves falling from a plant, or petals falling from flowers.

Some senescent cells can get sidetracked on the journey to “falling off” (in this case from our tissues). These cells become experts at surviving, exploiting normal cellular prosurvival functions to linger, loitering and taking up space in tissues. This would be somewhat analogous to yellowing leaves that haven’t fallen off a plant yet.

Because it’s normal to have some senescent cells start, but not complete the “falling off” journey, tissues need a back up plan. The backup plan is the immune system, which should act a bit like a gardener who prunes away the yellowing leaves on a plant. 

One of the jobs of the immune system is to find loitering senescent cells and remove them. When the immune system is adept at finding and removing these cells, the pace of removal maintains a healthy balance with creation. This is where aging enters the story.

When we are young, the immune system will typically be great at finding, and figuratively speaking, pruning away senescent cells. As we get older, the immune system tends to gradually become less proficient in lots of different ways; one of these is finding and pruning senescent cells—some senescent cells may get missed. Over time, this can result in gradual accumulation of senescent cells.

Senescent cells are often described as being “zombie cells.” This is because, not unlike the undead zombies in movies, a senescent cell can get stuck in a kind of limbo. It has one more thing in common with movie zombies: senescent cells can convince otherwise healthy cells to become senescent cells, which may add to the accumulation burden.

But why is the accumulation of senescent cells important? It comes down to a fundamental principle—the health of tissues depends on the health of the cells in those tissues. What do you think might happen if space that should be filled with healthy cells is being taken up by loitering senescent cells instead? The answer is very similar to what occurs if a plant has a growing number of yellowing leaves taking up space on its branches. 

There are a few main reasons gardeners prune leaves: (1) pruning allows resources and nutrients to be used in healthy, vibrant leaves rather than being poorly invested in less healthy ones; (2) pruning encourages new growth; and (3) pruning promotes the overall health and appearance of a plant. This is where senolytics come in; they can be thought of as a way to prune away the equivalent of yellowing leaves in our tissues.* 

The word “senolytic” is derived from the Latin words senex (=old) and lytic (=destroying). They are aptly named. Senolytics have an affinity for finding cells that are using senescent cell prosurvival mechanisms, and then convincing them to finish the journey to “falling off” instead.*

Now let’s answer the original question—What is Qualia Senolytic? It is a senolytic supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. It does this by, figuratively speaking, pruning away senescent cells. Its goals are similar to those of pruning a plant: support efficient use of cellular resources, encourage growth of more youthful cells by making “room” in tissues for them, and ultimately to support tissue health and appearance—promoting whole-body rejuvenation.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

The Soybean Seed Extract used in Qualia Senolytic contains soy isoflavones. Soy isoflavones are a type of bioflavonoid, which is often described as being a phytoestrogen. “Phyto” means plant, so phytoestrogens are plant-based compounds that mimic some estrogen functions in the body. 

Many foods, especially legumes, nuts, seeds, and fruits contain phytoestrogens. While phytoestrogens are often described as having estrogen-like activity, scientific evidence suggests they have more of a normalizing or balancing role on estrogen function.* 

As is the case with most compounds found in the diet, it’s useful to think in terms of amount rather than good or bad. The amount of soy isoflavones in a 2-day dose of Qualia Senolytic would be similar to the amount consumed over about 1 week in a diet where fermented soy products are consumed consistently, like the Japanese diet, which has a reputation of being one of the world’s healthiest cuisines.

While there are no special instructions for getting started with senolytic supplements, a good way to introduce anything new is to start small and increase over time. 

Rather than taking the full recommended dose of 6 capsules a day on 2 back-to-back days during the first month, it’s fine to start by taking a lower dose and spreading it out over a few more days, or to start at a lower dose and eventually build up to the recommended dose. 

The nine high purity herbal senolytics used in Qualia Senolytic do not provide any significant amount of the caloric units of energy found within food (i.e., carbohydrates, protein, and fat). 

No. The Qualia science team believes the best approach to taking senolytic supplements is to follow a “hit and run” approach (i.e., take senolytics for up to several days in a row followed by a break of at least 2 weeks), but a “hit and run” approach can be achieved in several different ways. Our general recommendation is to take the monthly dose spread out over 2 days (this is the most common approach in ongoing studies*), but this should be considered as more of a guideline than an absolute rule. The monthly dose of Qualia Senolytic can also be spread out over 3-4 days or taken all on a single day, as examples. 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Our general recommendation is to take Qualia Senolytic with food. The reason for this recommendation is because (1) with food is the most common way senolytic supplements have been used in studies, and (2) Qualia Senolytic contains concentrated food extracts, some of which may be more bioavailable if taken with food.* 

When we tested Qualia Senolytic prior to launch, some participants chose to take it with food and others took it without food. So, if taking supplements on an empty stomach is something that you tolerate well and find more convenient, feel free to take it without food.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic contains a combination of nine vegan ingredients and was formulated to be taken on two consecutive days once a month. It was created to support healthy aging in an area called “cellular senescence.”* But what is that?

Aspects of cellular structure and function gradually shift in certain predictable ways as a normal part of the aging process. Scientists refer to nine of these gradual shifts as the Hallmarks of Aging—think of a hallmark in this case as meaning a distinguishing characteristic. Cellular senescence is one of the nine characteristics; it has to do with a special type of stressed or worn out cell called a senescent cell.

Senescent cells are created and removed from tissues constantly throughout life. They are formed as a routine part of normal healthy function. Muscle tissues, as an example, create senescent cells after intense exercise as part of recovery.

Senescent cells are also formed when a cell becomes so stressed or worn out that it’s not worth putting in cellular work to maintain or repair it (replacing it would be a better use of cellular resources).

As we get older, healthy creation and removal functions tend to shift in ways that result in gradual increases in the proportion of senescent cells in some, often many different tissues—removal functions fall behind. This occurs for two main reasons.

Senescent cells should proceed through a series of molecular steps in a biological process that got its name from the Greek word for “falling off,” in the sense of ripe fruit falling from trees, leaves falling from a plant, or petals falling from flowers.

Some senescent cells can get sidetracked on the journey to “falling off” (in this case from our tissues). These cells become experts at surviving, exploiting normal cellular prosurvival functions to linger, loitering and taking up space in tissues. This would be somewhat analogous to yellowing leaves that haven’t fallen off a plant yet.

Because it’s normal to have some senescent cells start, but not complete the “falling off” journey, tissues need a back up plan. The backup plan is the immune system, which should act a bit like a gardener who prunes away the yellowing leaves on a plant. 

One of the jobs of the immune system is to find loitering senescent cells and remove them. When the immune system is adept at finding and removing these cells, the pace of removal maintains a healthy balance with creation. This is where aging enters the story.

When we are young, the immune system will typically be great at finding, and figuratively speaking, pruning away senescent cells. As we get older, the immune system tends to gradually become less proficient in lots of different ways; one of these is finding and pruning senescent cells—some senescent cells may get missed. Over time, this can result in gradual accumulation of senescent cells.

Senescent cells are often described as being “zombie cells.” This is because, not unlike the undead zombies in movies, a senescent cell can get stuck in a kind of limbo. It has one more thing in common with movie zombies: senescent cells can convince otherwise healthy cells to become senescent cells, which may add to the accumulation burden.

But why is the accumulation of senescent cells important? It comes down to a fundamental principle—the health of tissues depends on the health of the cells in those tissues. What do you think might happen if space that should be filled with healthy cells is being taken up by loitering senescent cells instead? The answer is very similar to what occurs if a plant has a growing number of yellowing leaves taking up space on its branches. 

There are a few main reasons gardeners prune leaves: (1) pruning allows resources and nutrients to be used in healthy, vibrant leaves rather than being poorly invested in less healthy ones; (2) pruning encourages new growth; and (3) pruning promotes the overall health and appearance of a plant. This is where senolytics come in; they can be thought of as a way to prune away the equivalent of yellowing leaves in our tissues.* 

The word “senolytic” is derived from the Latin words senex (=old) and lytic (=destroying). They are aptly named. Senolytics have an affinity for finding cells that are using senescent cell prosurvival mechanisms, and then convincing them to finish the journey to “falling off” instead.*

Now let’s answer the original question—What is Qualia Senolytic? It is a dietary supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. It does this by, figuratively speaking, pruning away senescent cells. Its goals are similar to those of pruning a plant: support efficient use of cellular resources, encourage growth of more youthful cells by making “room” in tissues for them, and ultimately to support tissue health and appearance—promoting whole-body rejuvenation.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

There are no known supplement ingredients that need to be avoided on the days you take Qualia Senolytic.

Most polyphenols—fisetin included—are relatively poorly absorbed through the gut barrier. But science has been showing more and more that they can also act locally inside the gut and may exert effects through the gut-brain axis as well. So bioavailability is only part of the potential efficacy equation. Because of this, our science team puts much more weight on scientific studies evaluating body & brain responses over bioavailability. And, big picture, despite evidence suggesting poor bioavailability there are a lot of studies suggesting beneficial support for the brain & body even from poorly absorbed polyphenols. Even with quercetin, most of the senolytic studies to date have been with standard quercetin. We opted for Quercefit® because it was what was used in a human senolytic study, is being investigated in other human senolytic studies, and has been used in human clinical studies in other health areas (so has demonstrated brain & body support benefits)—so Quercefit® has much science behind it in addition to the evidence for its bioavailability.*

The data on the bioavailability of fisetin is a main reason that the Mayo Clinic chose to use a high dose of fisetin in their senolytic studies, and why we are recommending the 1400 mg/day dose of fisetin (which for a person of average weight matches the Mayo dose). In published animal studies of fisetin, oral fisetin in this human-equivalent dose range has supported the management of senescence cells, which is the main outcome we care about (not bioavailability). We think the recommended dose included in Qualia Senolytic is sufficient taking into account the data on fisetin’s low bioavailability, but we would not be as confident that the doses we've seen in other supplements claiming a senescent cell benefit (often 100 mg and sometimes a bit more) would provide the intended support.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Senolytic is vegan, gluten-free and non-GMO.

Yes. Qualia Senolytic was designed to complement Qualia Mitochondria+.

Women who are pregnant or nursing.

Children and teenagers under the age of 18.

Check with your doctor before taking Qualia Senolytic if…

• you are currently taking any prescription medications.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

If you notice something you think may be a side-effect, please stop taking Qualia Senolytic and let us know by email or by calling or texting (855) 281-2328.

The recommended dose for taking a senolytic supplement like Qualia Senolytic is 6 capsules a day on 2 consecutive days each month. 

This means that we recommend taking all the capsules in a box of Qualia Senolytic spread out over 2 days, followed by about 4 weeks where you won’t take any Qualia Senolytic capsules.

Qualia Senolytic does not contain any ingredients reported to interact negatively with alcohol.

Yes, ingredients in Qualia Senolytic support the body’s normal process of autophagy. That said, we'd think of supporting autophagy as a secondary benefit. The main intended benefit of Qualia Senolytic is managing senescent cells, which is not the same thing as autophagy. Autophagy and cellular senescence are two distinct cellular responses that can be activated by a variety of stresses and have to do with aging (so it's easy to confuse them). Both are needed to keep us healthy but they are different processes. 

Autophagy (literally meaning “self-eating”) is focused on degrading and recycling components inside cells and mitochondria (mostly damaged proteins and organelles). It helps maintain cellular homeostasis so that a cell does not become senescent (think of autophagy as an anti-senescence mechanism). Cellular senescence is about the whole cell and occurs when a cell has become so stressed and worn out that cleaning up some of the damage inside it is no longer sufficient. Instead of autophagy, a senescent cell needs to go through a "falling off" process (a healthy cellular function called apoptosis). Senolytic supplements are focused on supporting the whole cell to promote the completion of this falling off process. This is the main goal of Qualia Senolytic.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

It’s fine to take Qualia Senolytic less frequently than monthly for persons who prefer this, but the trade-off of less frequent dosing is getting less senolytic support. 

Taking Qualia Senolytic monthly is the dosing approach we recommend for adults of all ages who are already noticing or feeling some aspects of the aging process and would like healthy aging support. 

We consider once a quarter as being a useful option for persons who may be younger and/or not currently noticing/feeling the effects of the aging process but who would like support in managing senescent cells as a way to proactively promote healthy aging.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Soy foods and soy isoflavones have been studied a number of times and have not been found to impact testosterone in men.* 

As is the case with most compounds found in the diet, it can be useful to think in terms of amount rather than good or bad. The amount of soy isoflavones in a 2-day dose of Qualia Senolytic would be similar to the amount consumed over about 1 week in a diet where fermented soy products are consumed consistently, like the Japanese diet, which has a reputation of being one of the world’s healthiest cuisines.

Yes. We consider Qualia Senolytic to be compatible with intermittent fasting. It does not contain any significant amount of the caloric units of energy found within food (carbohydrates, protein, and fat) that may disrupt a fasting period.

During a water fast, or other types of periodic detox or cleanse protocols, a person may experience light headaches, lack of energy, slight irritability, gastrointestinal disturbances, or other mildly unpleasant symptoms. Similar experiences actually occur for a small percentage of people when taking a placebo in scientific studies. 

Put another way, many of the experiences thought of as being detox symptoms are not unusual and can occur for some people when doing something new (even an inert substance like a placebo). In our pre-market testing of Qualia Senolytic, detox symptom types of experiences occurred at about the same frequency as what would be expected from taking a well-tolerated dietary supplement or a placebo substance.* 

If you do notice any of these experiences and they are mild, make sure you are drinking plenty of water and consider taking a lower dose the next few times you take Qualia Senolytic. 

If you notice something you think may be a significant side-effect, please stop taking Qualia Senolytic and let us know by email or by calling or texting (855) 281-2328.  

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic contains nine plant extracts, seven of which we consider to be senolytics and two others we’d categorize as being senolytic complements (or potential senolytics).* 

Senescent cells are an example of complexity science; they use networks of cellular pathways (usually abbreviated as SCAPs) to resist being “pruned” away. But they can also use non-SCAP mechanisms—senescent cells are diverse and don’t all use identical survival strategies. 

And, some senolytic compounds appear to be more active in some tissues (and less active in others). 

Because of these interacting factors, Qualia Senolytic took a complex systems approach to managing senolytic supplements, selecting ingredients to address varying SCAP mechanisms (such as Fisetin and Quercetin), ingredients to complement them (such as milk thistle and soybean seed extracts), and ingredients for non-SCAP mechanisms (such as Piperlongumine) to holistically support managing senescent cells in a variety of tissues.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

It’s fine to wait to take a senolytic supplement like Qualia Senolytic until whatever time of day you eat your first food.

Our general recommendation for Qualia Senolytic does not take body weight into account, but it is perfectly fine to adjust the dose lower for any reason, including body weight. 

There is no best time of the day to take Qualia Senolytic, so feel free to take it with whatever meal is most convenient for you.

By our late 20’s, most of us will begin noticing changes caused by getting older. 

By our 40’s, we’ve gone beyond noticing …many of us are feeling aspects of the aging process. Some scientists believe that one of the reasons we notice and feel some aspects of (unhealthy) aging is because of stressed or worn out cells called senescent cells. Qualia Senolytic was formulated to support tissues in pruning away these senescent cells. Because senescent cells tend to gradually accumulate with the passing of years, Qualia Senolytic was created for adults in their 40’s and older or younger adults who may already be noticing or feeling the aging process.* 

Senolytic supplements, like Qualia Senolytic,  can also be taken periodically to support adults of all ages in managing senescent cells as a way to proactively promote healthy aging.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Senolytic should not be taken by children or teenagers. Qualia Senolytic was created to support healthy aging in adults, especially adults as they get into the age ranges where they are experiencing aging. By our late 20’s, most of us will begin noticing changes caused by getting older. 

By our 40’s, we’ve gone beyond noticing …we are usually feeling the aging process. Qualia Senolytic was created to provide support for these age groups and older.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Senolytic supplements should be thought of as a product that pays healthy aging dividends over time and with repeated cycles of use. In the pilot study we did of Qualia Senolytic prior to bringing it to market, the participants were between the ages of 32 and 66 and had at least a moderate degree of difficulty in comfortably performing a variety of activities of daily living (this is something that frequently accompanies aging). 

Most of the participants reported greater ease in comfortably performing these activities and less of the occasional stiffness that can accompany aging after two dosing cycles of Qualia Senolytic (i.e., after taking a full dose of Qualia Senolytic for 2 days, taking a few weeks off, and then taking another full dose of Qualia Senolytic for 2 days).* 

While this is one use case, we created Qualia Senolytic to support healthy aging in many areas (brain, muscles, immunity, joint, skin, etc.) so benefits may show up at varying speeds and in a variety of areas of function in different people depending on where aging is taking a toll.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Senolytic was designed to complement Qualia Energy Shot.

Yes. Qualia Senolytic was designed to complement Qualia Night.

During a water fast, or other types of periodic detox or cleanse protocols, a person may experience light headaches, lack of energy, slight irritability, gastrointestinal disturbances, or other mildly unpleasant symptoms. 

Similar experiences actually occur for a small percentage of people when taking a placebo in scientific studies. Put another way, many of the experiences thought of as being detox symptoms are not unusual and can occur for some people when doing something new (even an inert substance like a placebo). 

In our pre-market testing of Qualia Senolytic, detox symptom types of experiences occurred at about the same frequency as what would be expected from taking a well-tolerated dietary supplement or a placebo substance.* 

If you do notice any of these experiences and they are mild, make sure you are drinking plenty of water and consider taking a lower dose the next few times you take Qualia Senolytic. 

If you notice something you think may be a significant side-effect, please stop taking Qualia Senolytic and let us know by email or by calling or texting (855) 281-2328.  

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

While senolytic supplements do not need to be refrigerated, we recommend storing Qualia Senolytic in a cool dry place.

Qualia Senolytic has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2023, which means the expiration date for the bottle would be the end of April in 2023.

Yes. Qualia Senolytic was designed to complement Qualia Mind.

No. The Qualia science team believes the best approach to taking senolytic supplements is to follow a “hit and run” approach (i.e., take senolytics for up to several days in a row followed by a break of at least 2 weeks), but a “hit and run” approach can be achieved in several different ways.

Our general recommendation is to take the monthly dose spread out over 2 days (this is the most common approach in ongoing studies*), but this should be considered as more of a guideline than an absolute rule. The monthly dose of Qualia Senolytic can also be spread out over 3-4 days or taken all on a single day, as examples. 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Senolytic was designed to complement Qualia Skin.

Yes. Qualia Senolytic was designed to complement Qualia Vision.

Intermittent use—some experts call this a “hit and run” approach—is the way senolytic supplements are most commonly used to support healthy aging.* The “hit and run” approach means that senolytics are recommended to be taken for a couple of days followed by a longer period of time when they are not taken. 

Senescent cells are created in, and removed from tissues constantly throughout life (and over shorter periods of time like a month). The goal of taking senolytics is to shift the balance in favor of removal, which should not require daily dosing since senescent cells accumulate slowly.* 

Think about this “hit and run” dosing as being a bit like how you might approach pruning a plant: pruning is something you’d want to do frequently but not every day. Another way to think about taking senolytics is as being akin to a water fast or detox protocol, which are not something done every day, but instead, would be something done for a few days periodically to support health goals.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Yes, Qualia Senolytic can be taken with any other product within the Qualia line of supplements.

As we age, senescent cells accumulate, but where they accumulate, and what aspects of healthy function they may influence, can vary person-to-person: for some people it may be the skin, for other people it may be fat or muscle tissue, for others it could be the brain, joints, immune system, etc. Because of this, there is no one way that Qualia Senolytic is experienced.* 

With the above in mind, the areas you should expect benefits are the areas that are typically most impacted during aging, so pay attention to signs of healthier skin, muscles, joints and brain functions, as well as overall health and energy, after two-to-three months of taking a senolytic supplement like Qualia Senolytic.*   

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, cure, or prevent any disease.

Qualia Mitochondria+ was formulated to support cells in making energy and keeping healthy cells healthy through the aging process. It's something designed to be taken on most days of the month. Qualia Senolytic was formulated to support pruning away of unhealthy cells as we age. It's something designed to be taken two days a month. We consider them to be perfect complements, with Qualia Senolytic being taken on a couple of the monthly off days from Qualia Mitochondria+.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

We’ve taken care to avoid risky ingredients and to select dosages that are unlikely to have negative effects for most people. That said, this isn’t a placebo. The supplements in Qualia have real effects and there is a lot in here. Read the instructions and follow them. If something feels wrong, stop using it.

Qualia is intended for healthy adults, ages 18 and up.

Per our disclaimer: This product contains chemicals that should not be taken by people on MAO inhibitors, SSRIs, or any other psychiatric medicines. It should not be taken by people with psychiatric or neurologic disorders, high blood pressure, heart conditions, endocrine disorders, cancer, or people on immunosuppressive therapy. It should not be taken by pregnant or nursing mothers, or children under 18. 

Lifestyle
Qualia is intended to support cognitive function and productive flow states as a part of a lifestyle that promotes well being and optimal performance. Good nutrition, exercise, sleep, mental engagement, emotional management, and an empowered outlook are all essential for a healthy body and brain.

Cycling
Qualia was designed for regular use, with cycling: 5 days on and 2 days off each week. This maximizes the benefits while preventing desensitization. It does not matter if the 2 "off-cycle" days are consecutive or apart, so long as they happen each week. For maximum benefits, we recommend that people cycle off all caffeine (including this product) for one week every three months or so. Qualia can also be used fewer days per week, or on an as needed basis for immediate effects, but the longer term effects this product is designed to support require regular use over an extended period of time.

Sleep
Qualia is most effective in a rested brain and is not intended to enhance function during sleep deficit. Good sleep is crucial for optimal cognitive function. When you engage your brain more intensely, it can increase your need for sleep, as is the case with intense exercise. Please note many people describe their sleep cycle going through an adjustment process the first few days on Qualia. If you experience any lingering insomnia or sleep issue, you may want try taking Qualia earlier in the day or lowering the dosage, prior to ceasing use.

Instructions
The instructions matter! This is a powerful nootropic stack, taking it as intended is important.

*Please note, the following can impact or alter the effects of Qualia:

• Taking Qualia if contraindicated in the disclaimer may not be safe. 
• Taking Qualia too late in the day may interfere with sleep.
• Desensitization from other past stimulants, psychotropic drugs or meds may lessen the effects
• Not drinking enough water 
• Cannabis or alcohol use
• Caffeine desensitization

For some, Qualia can help them remember their dreams more vividly.

Vitamin B6 in phosphorylated form, (Vitamin B6 as Pyridoxal-5-Phosphate [P-5-P]), has been commonly reported to increase the lucidity of dreams. Many of the other brain nutrients and nootropic compounds found in our formulations also have some data reporting their impact on dreams. 

For additional insight into P-5-P and the other ingredients, why they were chosen, and the research behind them, please review our formulation section.

A very small percentage of people have reported some kind of headache or head pressure after beginning Qualia. If the headache feels severe or bothersome, discontinue use and contact us for a refund. If it simply feels like some pressure and you want to explore it, lower the dose and see how it feels.

Some people can get pressure in the head or correspondingly in the neck or jaw from elevating their levels of acetylcholine. There are a number of ingredients in Qualia that are designed to elevate acetylcholine. Some people are more sensitive to this than others. If that's the case, lowering the dose is often times enough to abate this.

Also, many people who did feel some head pressure at first continued with their experimentation at the same dose and reported that their headaches went away within a week as their bodies adjusted.

Increased Heart Rate

If you are particularly sensitive to having heart rate increase because you have a heart condition or tachycardia, Qualia might be contraindicated. Please refer to our medical disclaimer and consult with your doctor.

If it’s only mildly elevated, stop use for a day or two, and try again at a lower dose, if you like. 

Flushing

Qualia can increase circulatory function. A very small number of people might experience heat or redness in the skin or a sense of flushing. If it’s uncomfortable, discontinue use for a day or two and start again at a lower dose. For most people who experience this it will stop within a couple days.

Are there alternative ways to take Qualia capsules or tablets and still get a beneficial effect?

Yes!

You can open the Qualia capsules and take with water or even place under the tongue for quicker absorption. If stomach upset occurs, take them with food (smoothie, juice, soup, yogurt, etc). 

We do not recommend taking Qualia with any other psychoactive medication, such as Adderall.

You should consult your physician when discontinuing use of any psychoactive medication prior to using any product you are intending to replace the use of a psychoactive medication.

Many people have reported beneficial changes in mood and cognitive performance transitioning from some medications to Qualia, however, as there are many variables in each individual mental condition and treatment plan, consult your physician prior to any transitioning from any regimen onto any other.

As you get started with Qualia you will feel more energy, motivation and drive but may also experience other feelings around your emotions.

Feeling less emotional?

Are you less emotional, as in numb and disassociated, or are you just more grounded, clear-minded and non-reactive?

If you’re simply experiencing less angst and anxiousness, that's great. 

If you really feel numb or muted, discontinue use. This might not be the right formulation for you.

Feeling more emotional?

Are you feeling more emotional in a balanced and grounded way; feeling emotions more clearly or powerfully? If so, that's great. 

If you’re feeling emotionally unbalanced in a negative or overwhelming way, discontinue use. This may not be the right formulation for you. 

Feeling irritable?

You might feel edgy if the dose is too high. Try again at a lower dose.

Feeling over-energized?

The dose may be too high for you. We suggest taking a day off then trying again with a lower dose.  

Feeling tired or fatigued?

Feeling some fatigue when first starting is sometimes experienced by a small percentage of users. The brain uses glucose-energy faster than muscles do, so when someone is really up-regulating their cognitive utilization (as you are when taking Qualia), just like when someone starts working out a lot, they can feel tired and need more rest and repair time. 

For many, this fatigue abates as their bodies adjust within a week or 2. If it does not, and you find that this current formulation isn't the right match for your chemistry, let us know and we'll be happy to issue a refund.

Get good sleep. Eat well. Move your body. If you’re fading early in your productive workday, you can try a small secondary booster dose on an empty stomach. Also, make sure you are being realistic about how much you should actually be able to accomplish in one day.

As found in our medical disclaimer, Qualia should not be taken by women who are pregnant or nursing. 

Medical Disclaimer:

This product contains chemicals that should not be taken by people on MAO inhibitors, SSRIs, or any other psychiatric medicines.

It should not be taken by people with psychiatric or neurologic disorders, high blood pressure, cancer, or people on immunosuppressive therapy.

It should not be taken by pregnant or nursing mothers, or children under 18.

If any undesired side effects are noticed, it should be discontinued immediately, and proper medical help sought if needed.

No claims are made about the safety of this product, nor are any medical or psychological benefits claimed.

Consult with your physician before taking any new supplements.

Please review our terms and conditions and privacy policy for additional information.

The number one reason people may not feel the effects is lack of or poor sleep. Qualia works along the same pathways in the brain that move your memories from short to long term storage when you are in deep sleep.

If those pathways are blocked or unavailable due to lack of or poor sleep, you will not feel Qualia working.

If that is the case, the best advice is to stop taking Qualia and work on your sleep. Take 3-5 days and get as much sleep as you can. Rest up and then try Qualia again and see if you notice the difference.

Here is the rest of the best advice to get the most out of Qualia:

Qualia is going to be most effective in addition to a performance optimizing lifestyle, and least effective in a performance damaging lifestyle.

Things that can make it most effective:

• Follow the instructions.
• Get good sleep. If you’re not sleeping enough or well, the product will not work.
• Get good nutrition. Qualia is designed to work with additional chemistries not included in this stack that are part of any healthy diet. If you’re not eating well, this product might not work well.
• Get moving. Your body fluids need to circulate. If you’re not getting exercise and movement, it’s not going to work as well.

Things that can make it less effective:

• Not following the instructions
• Not enough healthy fats in your diet
• Caffeine desensitization
• Too small a dose
• Not drinking enough water
• Cannabis or alcohol use
• Desensitization from other past stimulants or psychotropic drugs or meds

The most common effects people report from Qualia Mind and Qualia Mind Essentials are increased focus and attention, increased memory and cognitive capacity, increased drive, motivation and positivity, and increased emotional resilience.

To further explore, check out our Product page, which outlines all the subjective and performative effects this product was designed to enhance, and the way we went about doing it.

Though not common, a small percentage of people who have taken Qualia have noticed some increased level of anxiety when initially taken. Typically these are people who also notice an increased level of anxiety from caffeine related sources. If you have a strong anxiety experience we suggest discontinuing Qualia use and contacting us for a refund, as this may not be the right formulation from you.

 If it is a milder experience on par with what you would experience with a cup of coffee and its something you would want to explore further, you can look at lowering or adjusting the dose accordingly. You may also choose to use Qualia in conjunction with more exercise, meditation and other activities that help address anxiety. Some people who are experienced neurohackers and want to dial in their own chemistry have reported choosing to take additional nutritional supplements (i.e. phosphorus, 5htp, magnesium 3 & 8, GABA, or other calming herbs along with Qualia, or, before bed) which help attenuate those kinds of experiences. 

If you feel well educated and wish to explore responsibly on your own, or if you have appropriate medical support to guide you in this, it may be a topic that you will want to address with them. Are you sensitive to caffeine? Please see our caffeine-free version.

Typically the standard recommended dose is applicable across the board except for a small percentage of people. Body weight can be one factor that requires dosage adjustment, as can highly sensitive or de-sensitized systems. With this in mind, we recommend starting with the standard dose, and then, if needed, making any adjustments from there.

To that end, quality sleep is actually more important than body weight when it comes to feeling the optimal effects. Qualia works along the same pathways in the brain that move your memories from short to long term storage when you are in deep sleep. If those pathways are blocked or unavailable due to lack of and/or poor sleep, you will not feel it working. We recommend that prior to taking Qualia (as well as while on it), be sure to work on your sleep and get as much rest as you, ensuring proper optimization and resulting effects, no matter what your body weight. 

The length of time to notice the effects can vary, but in general, you'll be able to feel the subjective, full effects as it relates to mental focus, energy and clarity within as little as 20 minutes. If you do not, and if your sleep is on par with the info outlined above, then we'd recommend increasing your dosage. 

Everyone's chemistry is unique, and if the standard dosage does not match for your needs, we encourage experimenting and adjusting to find your optimal intake. 

Parkinsons, Multiple Sclerosis, and Alzheimers are all very different conditions and those with these or any other neuro-degenerative conditions are contraindicated. To date, we have not done any clinical trials pairing Qualia with neurological conditions, and as such, have no data to share regarding its potential impact.

Per our medical disclaimer, Qualia should not be taken by people with neurologic disorders as we don't know the interactions.

As we are not in a position to offer medical advice advice, the best course of action is for you to talk with your personal healthcare provider, or a functional medicine doctor, for any questions related to pairing Qualia with your diagnosis and any potential contraindications therein. 

Minimal alcohol consumption, such as a glass of red wine in the evening, is generally well tolerated. Please note, however, that taking with heavy alcohol consumption is not recommended. And also note that exceptions do exist where any alcohol consumption can contribute to noticeable decrease in intended effect and benefit. This is a topic of empowered responsibility for you to explore.

Since recreational drugs are not legal in the United States, we are not in a position to advise regarding their interactions with Qualia. That said, many people in the biohacking and neurohacking forums have explored many different chemical combinations of various nootropics with cannabis, entheogens, etc. Feel free to go to forums that discuss this topic and learn from other people's experiences, and you can then develop a more informed opinion.

While we obviously can't say anything about use of scheduled narcotics, for safety sake we would encourage at least a 24 hour pause before and after other strong psychoactive chemistry and Qualia.

This review, by a member of the qualialife.community regarding their personal experience around this topic, may also be of interest and insight:

There are no ingredients that should conflict with any standard corporate drug test, nor is there any ingredients that is a controlled narcotic. 

Other regulatory bodies such as sports organizations and collegiate associations have their own rules and lists of banned or prohibited substances.  We strongly encourage you to research which substances are banned by any regulatory body that you participate under and check those against the ingredients in Qualia listed on our Formulation page before taking Qualia. 

There are a few ingredients in Qualia that could have a foreseeable conflict.  These ingredients are caffeine and phenethylamine.   Some regulatory bodies also ban any substance that is chemically related to the class, even if it is not listed as an example on their documentation, so please consult with that organization if you have any questions.

Qualia Life Sciences uses a model of science called complex systems science. One of the core principles is adaptation. Living organisms are experts at adapting to things. For this reason, Qualia formulations are designed to be taken 5 days on and 2 days off each week. This maximizes the benefits while preventing desensitization. It does not matter if the “off-cycle” days are consecutive or apart, so long as they happen each week. We recommend "cycling" for the following Qualia formulations: 

• Qualia Mind and Mind Caffeine Free

• Qualia Mitochondria+

• Qualia Night

If stomach upset occurs when taking the product on an empty stomach, take with a meal instead. 

Optimal dosage can vary based on body weight and sensitivity.

Did you drink alcohol with Qualia or mix it with other drugs?

Because of the GABAergic effects of alcohol mixed with Qualia, a small percentage of people could experience feeling a little spacey or trippy. Some users may also experience heightened effects of alcohol, such as feeling inebriated quicker, when taking Qualia. For these reasons, we don’t recommend taking Qualia within 24 hours of alcohol consumption.

We don’t recommend taking the product within 24 hours of psychoactive drugs either. If you plan on doing that, we suggest talking to a doctor about it first.

While Qualia is generally well tolerated by those using CBD oil, consult with your physician to make sure the specific medical condition for which you are taking CBD oil does not contradict with any ingredients in Qualia. 

Qualia was designed to be free of adverse side effects when taken appropriately. Qualia is not a placebo but is a powerful psychoactive with high-quality ingredients, so be please read and follow all of the instructions carefully. 

Please read the disclaimer in order to make sure this is the appropriate product for you.

Instructions for Qualia Mind

A small percentage of people may experience minor issues, such as headaches, sleep disturbance, muscle tightness, upset stomach or fatigue. Please review the troubleshooting section for information on how to resolve them.

If you have any questions or need help getting Qualia working best for you, please get in touch.

A small percentage of people have reported muscle tightness or soreness, particularly in the neck, shoulders or jaw. Some of those people may also report some sense of pressure in the head. This is most likely the result of choline sensitivity. People have various tolerances for choline and various choline sensitivities. There are a number of ingredients in Qualia that are designed to elevate acetylcholine levels. While this has many benefits, if it is more than someone's sensitivity is currently capable of processing, it can result in muscle tightness or soreness.

If it is intense or concerning, we recommend immediately discontinuing use and contacting us for a refund.

If it is mild and you want to explore further, you can try getting off the product for a few days to normalize and starting again at a lower dose and see if it is gone. Some people who have reported soreness reported that it went away even at a full dose after about a week because their bodies adjusted. These symptoms can also dissipate or disappear entirely after they started exercising more and actually utilizing more of the chemistry. These are all things you are welcome to explore.

Unfortunately, the chemistry of depression and anxiety can be very nuanced. As such, we do not recommend anyone experiencing any type of psychiatric issues take Qualia unsupervised. While some have reported that they have felt a brighter mood and more calmness after taking Qualia, we recommend further discussing this with your physician. Please also see our disclaimer below:

Medical Disclaimer:
This product contains chemicals that should not be taken by people on MAO inhibitors, SSRIs, or any other psychiatric medicines. It should not be taken by people with psychiatric or neurologic disorders, high blood pressure, cancer, or people on immunosuppressive therapy. It should not be taken by pregnant or nursing mothers, or children under 18. It should not be taken within a 24 hour time period from alcohol or recreational drugs. If any undesired side effects are noticed, it should be discontinued immediately, and proper medical help sought if needed.

No claims are made about the safety of this product, nor are any medical or psychological benefits claimed.

You should consult with your physician before taking any new supplements.

Some people experience a re-regulation of sleep patterns after the first week on Qualia. Some users may find they fall asleep later, or sleep less, or have more vivid dreams. If those experiences occur, they generally normalize within a week of regular use.

Because the product contains a small amount of xanthines (caffeine, theophylline, theobromine), we recommend taking Qualia at least 8 hours before bed, depending on how sensitive you are to xanthines and how quickly you metabolize them. 

Yes, some people might experience a sense of tingling, or heat or redness in the skin, or a sense of flushing when taking Qualia NAD+. 

Qualia NAD+ contains 3 different NAD+ precursors: (1) nicotinamide riboside, (2) niacinamide, and (3) niacin (nicotinic acid). The first two, nicotinamide riboside and niacinamide, are typically described as being non-flushing. The niacin (nicotinic acid) form of vitamin B3 can cause flushing; however, this usually only occurs when it is supplemented in amounts of 30 mg or more. In studies, it has been very rare to experience a niacin flush with 30 mg of nicotinic acid, but about half of people experience flushing when taking 500 mg of nicotinic acid. We formulated Qualia NAD+ to have less than 30 mg of the nicotinic acid form to reduce the chances of flushing—a 2 capsule serving of Qualia NAD+ only contains 20 mg of the flushing type of vitamin B3. Because of this, we expect flushing to be a rare experience when taking Qualia NAD+. But individual differences (i.e., genetics, gut microbiome, etc.) may make some people more prone to experiencing a niacin flush when supplementing even low amounts of nicotinic acid (and possibly even the non-flushing forms of niacin). Niacin flushing can be felt anywhere along a continuum of being a mild tingling sensation to feeling very uncomfortable—it can be experienced as feeling a lot like an allergic reaction. While it can be uncomfortable, a niacin flush is considered to be harmless and temporary, usually taking less than 1-2 hours to go away on its own. A general rule of thumb is that flushing is most intense after the first time someone takes a supplement containing nicotinic acid, and typically diminishes over days or weeks with continued use. However, flushing from low amounts of nicotinic acid can also occur sporadically and unpredictably. In other words, it's possible to take a supplement many times and never flush, and then one day experience flushing unexpectedly.*

If you experience a niacin flush after taking Qualia NAD+, and wish to continue taking it while decreasing the chance of flushing, our recommendation is to take 1 capsule rather than 2, and to retry the 2 capsule amount after several days to a week. If you continue to experience significant niacin flushing, Qualia NAD+ may not be a good fit for your unique biochemistry, and you may want to discontinue it and request your money back.

**These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.
 

Qualia NAD+ is a 2-capsule-per-day product that exclusively supports NAD pathways and helps bolster NAD levels. Qualia Mitochondria+ requires up to 8 capsules per day and provides NAD benefits while offering broader support for mitochondrial function, autophagy, stress management, and cellular metabolism.

The best time to take Qualia NAD+ is near the start of your day. Circadian (i.e., body clock) research in animals suggests that NAD+ boosting compounds offer better support for metabolic health when taken at the beginning of the day. And, studies indicate that NAD+ levels are circadian in nature and peak during the daytime. By taking Qualia NAD+ at the start of your day, you’ll be taking it in a way that coincides with these natural rhythms.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

It’s fine to take Qualia NAD+ without food, and it contains less than 1 calorie, so it is fine to take before eating your first food of the day.* If you do wait until later in the day to take it, please keep in mind that Qualia NAD+ does contain 28 mgs of caffeine, which is about the amount in a small coke.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Our suggested amount of Qualia NAD+ does not take body weight into account, but it is perfectly fine to take a lesser amount for any reason, including body weight. But keep in mind that for the best NAD+ benefits we recommend that 2 capsules (the suggested serving amount) be taken daily.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ does not contain any ingredients reported to interact negatively with alcohol.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ is designed to work beneath the surface (it's a cellular health supplement), so its primary purpose is not to deliver results you'd feel. That said, in the pre-market pilot study we conducted, most participants reported noticing benefits in one or more areas related to energy, mood, or sleep after 10 days of taking Qualia NAD+. But keep in mind that results may vary from person to person.*   

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

At the time we formulated Qualia NAD+, the FDA had determined that NMN (nicotinamide mononucleotide) was excluded from the definition of dietary supplement, which essentially means it was not allowed to be sold as an ingredient used in a dietary supplement. NMN was not in our product because Qualia NAD+ is a dietary supplement. 

While that decision has since been reversed by the FDA, at this time, we do not have a plan to reformulate Qualia NAD+.

If you're interested in doing a deeper dive into the formulation of Qualia NAD+ and how it is uniquely formulated to support the body's innate capacity to produce, utilize, recycle NAD+, and ultimately sustain healthy NAD+ levels*, please take a look at the formulation page found here: https://www.qualialife.com/the-formulator-s-view-of-the-qualia-nad-ingredients

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ is an NAD+-boosting dietary supplement that provides several precursors for NAD+ production along with compounds that support rate-limiting steps in NAD+ biosynthesis. Qualia NAD+ was designed to support intracellular levels of NAD+.* NAD+ IV therapy consists of the administration of NAD+ directly into the bloodstream, which means it primarily boosts extracellular NAD+.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, Qualia NAD+ works. Qualia NAD+ clinically is proven to boost NAD+ levels by 67%^*‡ This suggests it is effective at boosting NAD+ levels in the body.

‡ Based on double-blind placebo-controlled studies. Individual results may vary. Full study results at qualialife.com/nad-clinical2. 

NAD+ (nicotinamide adenine dinucleotide) is not the same as vitamin B3, but it is derived from it. Vitamin B3 (niacin, nicotinamide, or nicotinic acid) is a precursor that the body converts into NAD+, a vital coenzyme involved in energy production, DNA repair, and cell signaling*.

Qualia NAD+ is a daily supplement that is uniquely formulated to support the body's innate capacity to produce, utilize, recycle NAD+, and ultimately sustain healthy NAD+ levels. This is important because NAD+ levels gradually decline with age, and adequate levels of NAD+ are needed to support cellular energy production and to keep cells healthy.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ is designed to work beneath the surface (it's a cellular health supplement), so its primary purpose is not to deliver results you'd feel. That said, “energy”  (i..e, having more energy, feeling more energetic. etc.) is the theme we most commonly get as anecdotal feedback. A more balanced mood (i.e., less moody or irritable, more calm. etc.), sleep (i.e, needing a bit less, feeling better rested, etc.) and general well-being are other areas that can be experienced. But keep in mind that everyone is unique and results vary from person to person.*   

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

The suggested serving of Qualia NAD+ is intended to be taken once daily to experience NAD+ benefits.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

We recommend that Qualia NAD+ be taken all at once early in the day. This is for 2 reasons. One reason is that Qualia NAD+ contains caffeine from Coffeeberry®, with a full serving having 28 mg of caffeine. While this amount is less than the caffeine in, for example, a 12 ounce coke, it is enough that it may disrupt sleep in some people if taken later in the day. The second reason is that research suggests that to experience NAD+ benefits the best time of day to take NAD+ boosting compounds is at the beginning of our day.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia NAD+ was designed to complement Qualia Probiotic+.

We recommend taking 2 capsules every morning to experience benefits of NAD. They can be taken with or without food.

There are no special instructions for getting started with Qualia NAD+. Our general recommendation is to simply start by taking 2 capsules with water or a beverage of your choice in the morning, with or without food.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia NAD+ can be taken while intermittent fasting. It contains less than 1 calorie, which most experts believe is not enough food energy to disrupt a fasting window.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

If you notice something you think may be a side-effect, please stop taking Qualia NAD+ and let us know by email or by calling or texting (855) 281-2328.

Tru Niagen contains NIAGEN® Nicotinamide Riboside. Qualia NAD+ contains the same NIAGEN® Nicotinamide Riboside and also has two other NAD+ precursors, plus the entire B-Complex family of vitamins, Magnesium, Resveratrol, and Coffeeberry®.

Qualia NAD+ is intended for adults. It was formulated to support healthy levels of NAD+ and experience NAD+ benefits. NAD+ levels decline naturally as we age. Children and teenagers typically have healthy levels of NAD+, so we do not recommend Qualia NAD+ for them.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia NAD+ was designed to complement Qualia Vision.

Yes. Qualia NAD+ was designed to complement Qualia Skin.

Yes. Qualia NAD+ was designed to complement Qualia Nootropic Energy Shot.

Yes. Qualia NAD+ was designed to complement Qualia Resilience.

Yes, Qualia NAD+ can be taken with any other product within the Qualia line of supplements.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Any adult looking for ways to support their long-term health as they age is an ideal candidate. Qualia NAD+ was formulated to support optimum levels of NAD+ as we age. Some people have suboptimal NAD+ levels at younger ages. Many of us will experience a sharp decline in NAD levels by around thirty years of age. The vast majority of people in their 40’s are relatively low in NAD+ compared to a healthy 20 year-old. If you're 50+ years old or older, you likely have about half or less of the NAD+ levels you had when you were younger in at least some of our tissues. As always, we recommend consulting with your physician prior to use if you are pregnant or nursing, taking any medications or have any diagnosed medical conditions.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. It's fine to take only 1 capsule instead of 2; however, for the best NAD+ support we recommend that 2 capsules (the suggested serving amount) be taken daily.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia NAD+ was designed to complement Qualia Mitochondria+.

Yes. Qualia NAD+ was designed to complement Qualia Senolytic.

Women who are pregnant or nursing.

Persons who have allergies or sensitivities to any ingredients in Qualia NAD+.

Check with your doctor before taking Qualia NAD+ if…

• you are currently taking any prescription medications.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

Yes. Qualia NAD+ was designed to complement Qualia Mind.

Yes. Qualia NAD+ is vegan, gluten-free and non-GMO.

We recommend storing Qualia NAD+ in a cool dry place, but it does not need to be refrigerated. 

There are no specific supplements you should avoid while taking Qualia NAD+.* Consult your physician if you are taking any supplements at his or her recommendation.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

A serving of Qualia NAD+ contains less than 1 calorie.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ combines NIAGEN® nicotinamide riboside, with niacin and niacinamide. Cells use these three precursors in different ways to make NAD+. We wanted to make sure they had a supply of each. Qualia NAD+ was also formulated to support the work needed to transform NIAGEN®, niacin, and niacinamide into NAD+ by supplying Coffeeberry®, resveratrol, magnesium, and the entire family of B-vitamins. Other NAD+ boosting supplements ignore this cellular work; Qualia NAD+ makes supporting it a priority.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

Yes. Qualia NAD+ was designed to complement Qualia Night.

NAD+ is a critical molecule found in every cell in your body: it’s involved in hundreds of metabolic processes. NAD+ is most well-known for being involved in turning the energy in food into cellular energy (it’s a key player in metabolism) and regulating cellular functions related to maintenance, repair, and stress. Your health starts with your cells; their health creates your health. And, cells need adequate amounts of NAD+ to support many of the metabolic processes they rely on to stay healthy. NAD+ became an area of much greater scientific interest because of two things: the realization that NAD+ levels decline with age and the recognition that one of the NAD+ benefits is more youthful levels supports cellular health.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia NAD+ does not need to be taken with food. It can be taken on its own away from food, or it can be taken just before, during, or after a meal. Ingredients found in Qualia NAD+ (vitamins and caffeine) may cause upset stomach and nausea in sensitive individuals when taken on an empty stomach, so the supplement may need to be taken with food in this event.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Children 8 and younger should not take Qualia Magnesium+ because the amount of magnesium in a single capsule is greater than the recommended daily allowance for their age.

Check with your doctor before taking Qualia Magnesium+ if…

• you are currently taking any prescription medications—some medications may interact with magnesium.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

Qualia Magnesium+ can be taken by children (ages 9 and over), adolescents, and adults wanting to increase their daily magnesium intake. As always, we recommend consulting with your physician prior to use if you are pregnant or nursing, taking any medications or have any diagnosed medical conditions.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Magnesium supplements can be taken at any time of day. Some people prefer to take magnesium in the morning with breakfast (or lunch), while others prefer taking magnesium with dinner. It’s also fine to take 1 capsule of Qualia Magnesium+ with breakfast and another capsule with dinner.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

If you notice something you think may be a side-effect, please stop taking Qualia Magnesium+ and let us know by email or by calling or texting (855) 281-2328.

Yes. Qualia Magnesium+ can be taken in addition to Qualia Skin®.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Magnesium+ has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

We recommend taking 2 capsules of Qualia Magnesium+ daily for adults and adolescents 14 years old and older. For children ages 9-13 years old, our suggested serving is 1 capsule daily. While they can be taken with or without food, magnesium may be better absorbed if taken with food, and taking it with food can make it more tolerable for persons with sensitive digestion.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Magnesium+ is a daily magnesium supplement that combines 10 different types of bioavailable magnesium, 70+ minerals and trace minerals from seawater, 7 amino acids and organic acids, and boron (to support magnesium absorption and retention). We think of this combination of different types of magnesium and trace minerals as magnesium the way nature intended it, because the two sources of dietary magnesium—food and magnesium-rich water—contain trace minerals.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

While magnesium has many functions in the body, some of the most common benefits of Qualia Magnesium+ include support for calmer moods, easing tense muscles, promoting restful sleep, soothing feelings of stress, and facilitating recovery from exercise.*   

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

It’s fine to take Qualia Magnesium+ with your first meal of the day or at a later meal.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

It can be useful to take magnesium with food for two reasons: 1) magnesium may be better absorbed when taken with food, and 2) magnesium may be more likely to contribute to loose stools when taken on an empty stomach.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

No, our suggested amount of Qualia Magnesium+ does not take body weight into account, but it is perfectly fine to take a lesser amount for any reason, including body weight. While the Institute of Medicine does not use body weight to determine recommended daily allowances of magnesium, persons with higher body weight may require greater amounts of magnesium in their diet to maintain healthy levels than people of significantly lower body weights.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, Qualia Magnesium+ is vegan, gluten-free and non-GMO.

Yes, it’s fine to take one capsule earlier and one capsule later in the day.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Magnesium+ does not contain any ingredients reported to interact negatively with alcohol.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

The amount of magnesium in 2 capsules of Qualia Magnesium+ is 350 mg; there is 175 mg of magnesium in 1 capsule. Qualia Magnesium+ should not be taken by children 8 years old and younger, because 1 capsule supplies an amount of magnesium greater than the upper limit set by the National Institutes of Health Office of Dietary Supplements for children 8 and younger. The Recommended Dietary Allowance (RDA) for ages 9-13 years old is 240 mg of magnesium, so we recommend taking only 1 capsule of Qualia Magnesium+ daily if it is used for this age group. For ages 14-18 years old, 2 capsules of Qualia Magnesium+ contain the upper limit of magnesium from dietary supplements and are below the RDA, so can be used to supplement the diet in this age group.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Magnesium supplements aren’t necessarily noticed or felt. Whether or not a person would notice a benefit can depend on many interacting factors including their magnesium status when beginning supplementation, diet, exercise levels, sleep habits, stress, use of medications, and other factors. That said, magnesium supplements gradually support tissue magnesium status, so benefits, when noticed, tend to be gradual and occur over several weeks.*   

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

There are no special instructions for getting started. Our general recommendation is to simply start by taking 1-2 capsules with water or a beverage of your choice with food.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

We recommend taking Qualia Magnesium+ every day, but how you do this is up to you. Some people may prefer to take one capsule of magnesium twice a day at different meals. This approach may increase the absorption of magnesium. Other people like to take both capsules at the same time—dinner can be a great time to take Qualia Magnesium+ when you want to take both capsules at the same time.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Magnesium+ does not contain any calories.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Magnesium is used in more than 600 enzymes in the body. Processes including making neurotransmitters for the brain, creating energy in cells, using energy throughout the body, and responding to stress rely on adequate intake of magnesium. Magnesium is critical for the gut microbiome, as well as bone, brain, heart, immune, and muscle health. All twelve of the hallmarks of aging may be impacted by magnesium. Qualia Magnesium+ was created to support all of these and more. It does this by supplying 10 forms of bioavailable magnesium and the full-spectrum of minerals and trace minerals it contains—in food and water, magnesium is never alone; it’s always with other naturally occurring minerals. Qualia Magnesium+ works by giving your body forms of magnesium it can readily absorb and use along with trace minerals that naturally occur with magnesium in water and food.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

We recommend storing Qualia Magnesium+ in a cool dry place, but it does not need to be refrigerated.

Yes, Qualia Magnesium+ can be taken while intermittent fasting. It contains no calories. Some experts suggest that minerals and trace minerals, both of which are found in Qualia Magnesium+, may be helpful when supplemented during fasting time periods.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Probiotic+ contains 33 mg of magnesium per serving. A full daily serving of both products contains 383 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Night® contains 50 mg of magnesium per serving. A full daily serving of both products contains 400 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Mind® contains 84 mg of magnesium per serving. A full daily serving of both products contains 434 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

There are no specific supplements you should avoid while taking Qualia Magnesium+.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Life® contains 48 mg of magnesium per serving. A full daily serving of both products contains 398 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Magnesium+ can be taken in addition to Qualia Focus®.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Energy Shot contains 25 mg of magnesium per bottle. A full daily serving of both products contains 375 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, taking 1 instead of 2 capsules is fine and is still a great way to supplement your diet with extra magnesium. A one capsule serving supplies about 44% of the recommended daily allowance (RDA) of magnesium for men 19-30 years old and 56% for women in that age range. For people ages 31 and older, 1 capsule of Qualia Magnesium+ supplies about 42% of the RDA for men and 55% for women.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Magnesium+ can be taken in addition to Qualia Senolytic®.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Deepak Chopra is a verified Qualia partner and endorses Qualia Magnesium+, stating that he personally takes it and appreciates its formulation. He highlights magnesium’s importance for bone, heart, muscle, immune health, and healthy aging, and recommends Qualia Magnesium+ as a supplement that “gets magnesium right.”*

Magnesium is an essential mineral in the body, supporting the activity of over 600 enzymes by acting as a cofactor, and is involved in most major biochemical and metabolic pathways in our cells. A few of the most common benefits of Qualia Magnesium+ include support for balanced moods, easing tense muscles, promoting restful sleep, soothing feelings of stress, and facilitating recovery from exercise.* Learn more about the benefits of magnesium.

Two capsules of Qualia Magnesium+ contain 350 mg of magnesium and Qualia Resilience® contains 40 mg of magnesium per serving. A full daily serving of both products contains 390 mg of magnesium. The National Institutes of Health Office of Dietary Supplements recommends that magnesium from dietary supplements not be consumed in amounts above 350 mg unless recommended by a healthcare provider. If you are going to take both products, taking 1 capsule per day of Qualia Magnesium+ would keep you below the upper limit of 350 mg.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, Qualia Probiotic+ can be taken with any other product within the Qualia line of supplements.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Many live probiotics are fragile, and are perishable when unrefrigerated. But the spore forms we use in Qualia Probiotic+—Lactospore® Bacillus coagulans, Bacillus subtilis, and Bacillus clausii—are very stable at room temperature and do not require refrigeration.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

If you notice something you think may be a side-effect, please stop taking Qualia Probiotic+ and let us know by email or by calling or texting (855) 281-2328.

Qualia Probiotic+ has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

You should expect to notice benefits in the performance of your digestive system. Qualia Probiotic+ was formulated to offer support in the five major areas of occasional digestive system complaints—abdominal discomfort, hard stools, indigestion (gas, bloating, etc.), loose stools, and upper GI discomfort. Some people experience a temporary increase in gas or bloating when starting products with prebiotics or probiotics—Qualia Probiotic+ contains both—that can last 1-2 weeks as the gut ecosystem adjusts.*   

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Some people can experience an increase in gas or bloating when starting products containing prebiotics and/or probiotics. This usually is temporary, and returns to normal within several days to two weeks, as a person’s gut bacteria adapt to these new additions to the diet.* If you experience an increase in gas or bloating after starting Qualia Probiotic+, we suggest decreasing the amount you take to ¼ or ½ a serving while your gut ecosystem is adapting. If uncomfortable increases in gas and bloating persist past a couple weeks, Qualia Probiotic+ may not be the right product for you. Contact us about our money back guarantee if this is the case.  

The suggested amount of Qualia Probiotic+ is one scoop per day. Feel free to mix it with 8 oz of water, juice, smoothie, or beverage of your choice. 

It’s fine to take Qualia Probiotic+ after whatever time of day you eat your first food.

Qualia Probiotic+ does not need to be taken with food. It can be taken on its own away from food, or it can be taken just before, during, or after a meal.

Yes. Qualia Probiotic+ is vegan, gluten-free and non-GMO.

Yes. Qualia Synbiotic was designed to complement Qualia Vision.

Yes. Qualia Probiotic+ was designed to complement Qualia Nootropic Energy Shot.

A serving of the unflavored version of Qualia Probiotic+ contains 20 calories. The flavored version of Qualia Probiotic+ contains 30 calories per serving.

Yes. Qualia Probiotic+ was designed to complement Qualia Mitochondria+.

We recommend storing Qualia Probiotic+ in a cool dry place, but it does not need to be refrigerated.

Some people avoid potatoes (or other plants in the nightshade family) because of concerns that they may contain glycoalkaloids (e.g., ɑ-solanine, ɑ-chaconine) or lectins. Glycoalkaloids are nitrogen-containing and lectins are proteins. SolnulTM is obtained via the collection of starch slurry from cut raw potatoes, which is then filtered, washed, and dewatered into a dry powder. The result is a product that is considered to be 100% potato starch (i.e., the proteins have been removed) and has had the glycoalkaloids reduced to levels below oral bioavailability.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Synbiotic was designed to complement Qualia Resilience.

Yes. It's perfectly fine to take less than the suggested one scoop daily. You can always start with a lesser amount and then work your way up to a full scoop for optimal digestive and gut microbiota support.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

We think of Qualia Probiotic+ as your all-in-one support for healthy gut performance. It combines three different species of probiotics, with four different prebiotic fibers, three postbiotic ingredients, twelve fermented berries and herbs, five digestive enzymes, and additional gut-brain supporting minerals and ingredients. A serving is high in fiber and only uses FODMAP friendly fibers.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides and polyols. The F and O in FODMAP stand for fermentable oligosaccharides like inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS). The D stands for disaccharides, with lactose being an example.* M stands for monosaccharides; these are the simplest of sugars like fructose. A is for “and.” The P stands for polyols (also known as sugar alcohols). FODMAP friendly (or low FODMAP) means that the amount of these compounds in a serving is low. Some people with sensitive digestive systems feel better when they follow a low-FODMAP diet or, put another way, they try to eat FODMAP friendly foods. The primary fibers in Qualia Probiotic+ are SolnulTM and Sunfiber®. SolnulTM is FODMAP friendly certified and Sunfiber® is a Monash University Low FODMAP certified™ fiber. Consult your physician if you are following a low-FODMAP diet at his/her recommendation.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

While the product is labeled as “Qualia Probiotic+ is intended for use by healthy adults, over 18 years old,” the Qualia science team believes the ingredients at the amounts in a suggested serving would allow this product to be safely used for school-age children (5+ years old) and teenagers. Just be sure to consult your child’s pediatrician before giving them any supplements.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

There are no specific supplements you should avoid while taking Qualia Probiotic+. Consult your physician if you are taking any supplements at his or her recommendation.

When it came to formulating Qualia Probiotic+, the goal was to help maintain a healthy gut ecosystem, to support balance and resilience. Probiotics help support this …so do postbiotics. We wanted to also promote the healthy growth of keystone gut microbiota, species that have disproportionately large effects on the gut ecosystem. 

This guided our selection of prebiotics. We wanted to support diversity and richness, so we included both a variety of prebiotic fibers, and also twelve fermented foods. The overwhelming majority of gut microbiota live in the lower gastrointestinal tract (GIT). But digesting food mostly occurs in the upper GIT. And, if the upper GIT is not performing its job, the lower GIT is impacted. So we included digestive enzymes to create a formula designed to support both the upper and lower GIT.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. If you want to take half of a scoop of Qualia Probiotic+ earlier and half later in the day that would be fine.

Resistant starch is the portion of starch that is “resistant” to digestion, escaping enzymatic action and absorption in the small intestine. It is more fiber-like, being poorly absorbed, and instead is used as a prebiotic fiber. The Solnul™ Resistant Potato Starch in Qualia Probiotic+ is 60% resistant starch, having a lower glycemic index than regular potato starch.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Best results with Qualia Probiotic+ will be obtained if it is added to room temperature or cooler water or beverages. One of the ingredients in Qualia Probiotic+ is called Solnul™ Resistant Potato Starch. This type of resistant starch is sensitive to heat and can lose some of its prebiotic action if it is exposed to hotter temperatures.  

Our suggested amount of Qualia Probiotic+ does not take body weight into account, but it is perfectly fine to take a lesser amount for any reason, including body weight. 

Qualia Probiotic+ does not contain any ingredients reported to interact negatively with alcohol.

Women who are pregnant or nursing.

Persons who have allergies or sensitivities to any ingredients in Qualia Probiotic+.

Check with your doctor before taking Qualia Probiotic+ if…

• you are currently taking any prescription medications.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

Some experts believe anything less than 50 calories will not break an intermittent fasting window. Other experts think any amount of calories, no matter how small, disrupts the fasting process. Both the unflavored and flavored versions of Qualia Probiotic+ contain less than 50 calories per serving, so meet the criteria some experts follow but not others.

Yes. Qualia Probiotic+ was designed to complement Qualia Skin.

We suggest taking Qualia Probiotic+ most days—a general goal should be 5 servings a week. Persons wanting more digestive support may want to take a serving of Qualia Probiotic+ every day.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Our general suggestion is to follow the suggested serving instructions of 1 scoop mixed with water or a beverage of your choice. But, some people like to start with a smaller amount when beginning a new supplement that contains prebiotics—Qualia Probiotic+ does—and gradually increase their daily consumption to the suggested serving size over a week or two.

In the pre-market pilot study we conducted, most participants reported noticing benefits in one or more occasional digestive system complaints (e.g.,abdominal discomfort, bloating, gas, hard stools, loose stools, and upper GI discomfort) after seven days of taking Qualia Probiotic+.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

There is no best time of the day to take Qualia Probiotic+, so feel free to take it at whatever time is most convenient for you.

Yes. Qualia Probiotic+ was designed to complement Qualia Mind.

Qualia Probiotic+ was formulated to support healthy digestive function, gut microbiota, and the gut-brain axis. Most of us can benefit from support in these areas, but people with occasionally digestive system complaints (bloating, gas, hard stools, etc.) and/or mood imbalances were who we specifically had in mind when we created Qualia Probiotic+.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Probiotic+ was designed to complement Qualia Night.

Yes. Qualia Probiotic+ was designed to complement Qualia Senolytic.

Taking a probiotic every day can help support a healthy balance of gut bacteria, supporting digestion, immune function, and overall well-being*. Some people may notice temporary side effects like mild gas or bloating at first, which usually subside as the body adjusts. Probiotics are generally safe for most people, but we always encourage checking with a trusted healthcare provider before adding any supplement to your routine. 

At Qualia Life, we believe that the best approach to support gut health is diversity—not only of probiotic species but also of supportive compounds such as prebiotics and polyphenol-rich plants. For example, adding prebiotics to a combination of probiotics may help enhance the benefits of probiotics. That’s because prebiotics, which are mainly dietary fibers that humans cannot fully digest, are digested and used as food by gut microorganisms, helping them grow and play their part in the gut ecosystem. Therefore, combining probiotics and prebiotics provides not only health-promoting microbes but also the fuel they need to do their job. This helps to create an optimal environment for beneficial gut microbes to thrive, and consequently, to support human health.*

Therefore, rather than choosing a specific probiotic species, combining a few species with prebiotics and other compounds that help to support gut health is, in our view, a more complete and beneficial approach to supporting a healthy gut microbiome and promoting balance and resilience within the gut ecosystem.

Qualia Probiotic+ is our solution to all-in-one gut health support. 

The primary benefits Qualia Joint Health provide include supporting joint and tendon health, helping with occasional soreness after everyday tasks and activities, supporting ease of movement and mobility, supporting healthy aging, supporting faster recovery from workouts and exercise, and helping to relieve temporary stiffness after strenuous workouts.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Joint Health does not contain any ingredients reported to interact negatively with alcohol.

Results from our beta study on Qualia Joint Health suggest individuals begin to experience benefits for joint health, function, and comfort within 7 days of supplementation, with even more noticeable effects over time. Several ingredients used in Qualia Joint Health—Ovomet®, Tamaflex®, ApresFlex®—have also offered fast-acting joint support in as little as 1 week. While these are the typical results from studies, individual responses can vary depending on many interacting factors including diet, exercise levels, sleep habits, stress, current health, age and more.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Calories are not a standard part of labeling for most dietary supplements, because, unlike foods, or macronutrients (e.g., fats, carbohydrates, proteins), vitamins, minerals, amino acids, and herbs don’t have clearly defined calorie counts. While we don't have exact calorie data, we’d estimate that a two capsule serving size of Qualia Joint Health may have about 3-4 calories.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

This doctor-formulated, innovative formula combines 10 advanced joint health nutrients and botanicals to: (1) supply a matrix of the biomolecules that support healthy collagen production and joint lubrication; (2) support the energy production joints rely on to maintain, repair, and lubricate themselves; (3) support balanced COX and LOX enzyme activity to foster fast-acting joint comfort; (4) support balanced immune signaling and the gut-immune axis; and (5) promote healthy digestion and the gut-joint axis.*

[Note: The gut-joint axis is the idea that the gut and joints interact, with gut health impacting joint health through mechanisms including the gut microbiome, gut immunity, and gut-derived metabolites.]*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Joint Health was designed to complement Qualia Senolytic®.

Yes. Qualia Joint Health was designed to complement Qualia Magnesium+.

Yes. Qualia Joint Health was designed to complement Qualia Night®.

There are no supplement ingredients that are known to interact negatively with Qualia Joint Health.* However, please check with your doctor before starting any new supplement regimens.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

There are no special instructions for getting started with Qualia Joint Health. Our general recommendation is to simply start by taking 1-2 capsules with water or a beverage of your choice with food.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Joint Health was designed to complement Qualia NAD+®.

It’s fine to take Qualia Joint Health with your first meal of the day rather than earlier in the morning.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Joint Health was designed to complement Qualia Mind®.

Qualia Joint Health can be taken at any time of the day, but our general recommendation is to take both capsules in the morning. 

Qualia Joint Health can be taken by adults (aged 18+) wanting to support their joint health and comfort. As always, we recommend consulting with your physician prior to use if you are taking any medications, or have any diagnosed medical conditions.

Yes. Qualia Joint Health was designed to complement Qualia Energy Shot®.

Qualia Joint Health has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

Qualia Joint Health is the next generation of support for joint comfort and mobility. Qualia Joint was formulated with potent extracts of Boswellia serrata, turmeric, ginger, tamarind, cucumber, and haritaki, as well as a nutrient-rich stack of eggshell membrane, L-carnitine and boron. This formula supports healthy joints and tendons, helps with occasional soreness after everyday tasks, promotes faster recovery from workouts, and supports healthy aging.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Qualia Joint Health can be taken with or without food.

Qualia Joint Health is gluten free and non-GMO, but is not vegan. The Ovomet® Eggshell Membrane used in Qualia Joint Health is made from upcycled eggs, so is not a vegan friendly ingredient. There are varying criteria and no official guidelines for what is meant by vegetarian: Ovomet® is considered suitable for vegetarians by its producer, and would be considered vegetarian by some people but may not be by others.* 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, it’s fine to take one capsule of Qualia Joint Health earlier and one capsule later in the day.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Women who are pregnant or nursing.

Children and teenagers under the age of 18.

Check with your doctor before taking Qualia Joint Health if…

• you are currently taking any prescription medications—some medications may interact with ingredients in Qualia Joint Health.

• you have a diagnosed medical condition.

• you are concerned about taking it for any reason.

If you notice something you think may be a side-effect, please stop taking Qualia Joint Health and let us know by email or by calling or texting (855) 281-2328.

We recommend storing Qualia Joint Health in a cool dry place, but it does not need to be refrigerated. 

Qualia Joint Health is recommended only for adults aged 18+.

Our general recommendation for Qualia Joint Health does not take body weight into account, because ingredients in the formula have been given at the same amounts to people of all body weights in human studies on them.* But it is perfectly fine to adjust the dose lower for any reason, including body weight. 

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes, Qualia Joint Health can be taken while intermittent fasting. We do not expect this formula or any of its ingredients to interrupt an intermittent fast.

Yes. Qualia Joint Health was designed to complement Qualia Mitochondria+.

Yes, taking 1 instead of 2 capsules of Qualia Joint Health is fine, but this lower serving size may provide less joint comfort benefits and will provide less overall support for healthy joints and tendons.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.

Yes. Qualia Joint Health was designed to complement Qualia Probiotic+.

Yes. Qualia Joint Health was designed to complement Qualia Focus®.

We recommend taking Qualia Joint Health daily, but how you do this is up to you. Some people may prefer to take one capsule of Qualia Joint Health twice a day at different meals, while others like to take both capsules at the same time. 

We recommend adults (aged 18+) take 2 capsules of Qualia Joint Health daily. 

Qualia Creatine+ contains 3 ingredients—OptiCreatine™ Creatine Monohydrate, Creatine MagnaPower® (supplying creatine and magnesium as a magnesium creatine chelate), and sea salt. The 2 types of creatine support its main function in cells which has to do with quickly replenishing ATP—the universal energy currency for cells. Creatine’s role in cellular energetics is especially important in tissues that have high and fluctuating energy demands such as muscle and brain, which is why the majority of studies on creatine are on exercise and cognition. The magnesium supports creatine’s function in ATP replenishment. Sea salt supports the creatine transporters used to move creatine into cells (in the brain, muscles, & intestines).*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Our suggested serving for adults (aged 18+) is 1 scoop of Qualia Creatine+ daily.

For best results we suggest taking 1 scoop of Qualia Creatine+ every day.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes, it’s absolutely fine to take less than the suggested amount. While the amount in 1 scoop of Qualia Creatine+ is intended to approximate the standard dose of creatine monohydrate used in many studies, creatine can be supplemented based on body weight. A dose of about ½ scoop would be in the general range of what’s sometimes described as a maintenance dose of creatine for an average weight person. So feel free to personalize Qualia Creatine+ for your needs and desired results.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

It is generally recommended to avoid creatine supplementation during pregnancy or when trying to conceive, unless specifically advised to take it by a healthcare provider.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Major medical societies and pediatric experts discourage creatine use in minors of all ages and recommend consulting a pediatrician or a sports dietitian if considering supplementing with it.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes, it’s fine to split the suggested serving size (1 scoop) into smaller amounts and take it whenever it is most convenient for you.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Creatine+ can be taken with Qualia Stem Cell.

Yes. Qualia Creatine+ can be taken with Qualia Mitochondria+.

Yes. Qualia Creatine+ can be taken with Qualia Mind®. But, you may want to consider taking them at different times. Some studies suggest that caffeine (in high amounts) may slightly blunt creatine’s ergogenic (i.e., exercise) benefits, while other studies have found there is no interaction, and others have reported a benefit of taking both together . Because of these mixed research findings, some experts suggest spacing out consumption (e.g., taking creatine post-workout and caffeine pre-workout as an example) and staying well-hydrated. Overall, the evidence leans toward safety and compatibility, especially at the amount of creatine in a suggested serving of Qualia Creatine+ and the moderate amount of caffeine in a serving of Qualia Mind®. Always follow recommended dosages for both substances.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Creatine+ can be taken with Qualia Magnesium+®.

Yes. Qualia Creatine+ can be taken with Qualia Mind® Caffeine Free. 

Yes. Qualia Creatine+ can be taken with Qualia Night®.

Yes. Qualia Creatine+ can be taken with Qualia Senolytic®.

Yes. Qualia Creatine+ can be taken with Qualia Probiotic+.

Yes. Qualia Creatine+ can be taken with Qualia Joint Health. 

Qualia Creatine+ contains 0 calories.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

While there are no special instructions for getting started with Qualia Creatine+, some people prefer to gradually introduce new supplements to give the body an opportunity to adjust to this new nutrition. For persons wanting to take a gradual approach, consider starting with ¼ scoop for a couple of days then increase to ½ scoop for a few more days before doing a full scoop daily.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

The most commonly studied benefits from taking creatine-containing dietary supplements such as Qualia Creatine+ have been improvements in muscle size and strength, high‑intensity exercise performance, and muscle recovery. Qualia Creatine+ also supports brain function and energetics, which for some individuals may be experienced in areas including focus, memory, mental clarity, mental energy, and a healthy mood.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. All of the ingredients used in Qualia Creatine+ are gluten free, non-GMO, and vegan.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

It’s fine to take Qualia Creatine+ with your first meal of the day rather than earlier in the morning.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Most people begin to notice muscle-related benefits from creatine supplementation—such as improved exercise performance or increased muscle size or strength—within 1 to 4 weeks of consistent use. Cognitive benefits in areas such as focus, memory, mental clarity, mental energy, and a healthy mood may be observed within 4 weeks. Individual results may vary depending on factors like diet, baseline creatine levels, sleep, and training habits.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes. Qualia Creatine+ can be taken with Qualia NAD+®.

If you notice something you think may be a side-effect, please stop taking Qualia Creatine+ and let us know by email or by calling or texting (855) 281-2328.

Yes, Qualia Creatine+ can be taken while intermittent fasting. We do not expect this formula or any of its ingredients to interrupt an intermittent fast.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Creatine+ is intended for healthy adults (aged 18+). As always, we recommend consulting with your physician prior to use if you are taking any medications, or have any diagnosed medical conditions.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

There is no best time to take it. Qualia Creatine+ can be taken at any time of day, and before or after exercise.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Qualia Creatine+ has an expiration date on the packaging. Look for EXP and a number, such as EXP 04/2025, which means the expiration date for the bottle would be the end of April in 2025, as an example.

Qualia Creatine+ was formulated to elevate the creatine experience by combining 2 advanced forms of creatine with 3 key electrolytes—magnesium, sodium, and chloride. A serving contains 5 grams from a combination of creatine monohydrate (as OptiCreatine™) and magnesium creatine chelate (as Creatine MagnaPower®). These two sources of creatine support hard working brain and muscle cells. A small pinch of salt is added to each serving to support creatine absorption and cellular uptake.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Moderate alcohol consumption is generally considered safe while taking creatine-containing supplements. However, alcohol may reduce the effectiveness of creatine by contributing to dehydration, which can impair muscle recovery and performance. To get the most benefits from creatine-containing supplements, some experts suggest that it may be advisable to limit alcohol intake and stay well-hydrated. If you have specific health conditions or concerns, consult a healthcare professional before combining alcohol with creatine or any supplement.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

High doses of caffeine may possibly interfere with creatine if both are taken together. Some studies suggest that caffeine (in high amounts ≥400 mg) may slightly blunt creatine’s ergogenic (i.e., exercise) benefits, while other studies have found there is no interaction, and others have reported a benefit of taking both together . Because of these mixed research findings, some experts suggest spacing out consumption (e.g., taking creatine post-workout and caffeine pre-workout as an example) and staying well-hydrated. Overall, the evidence leans toward safety and compatibility, especially at a more moderate amount of caffeine.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

While Qualia Creatine+ can be taken with or without food, best results for creatine are thought to occur when it is taken with a meal, beverage, or snack that contains carbohydrates, protein, or both. Taking creatine on an empty stomach can cause digestive issues (e.g., feelings of bloating or gas) in some people and these individuals sometimes tolerate it better when it is taken with food instead.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

We recommend storing Qualia Creatine+ in a cool dry place, but it does not need to be refrigerated.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Our general recommendation for Qualia Creatine+ (1 scoop) does not take body weight into account and approximates the 5 gram serving of creatine monohydrate that is a fairly standard dose in many human studies. But it is perfectly fine to adjust the dose lower for any reason, including body weight. Some experts use as a general rule of thumb for creatine dosing of around 5 grams daily as a standard dose (this would be about 1 scoop of Qualia Creatine+), with 2-3 grams for smaller individuals, and 7-10 grams for larger ones.* 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Yes, creatine can occasionally cause mild bloating. This is typically temporary and more likely to occur during the first several days after beginning supplementation. Creatine bloating is believed to occur because of water retention in muscles. When creatine intake is increased, the amount of creatine inside muscle cells rapidly increases. As muscles absorb more creatine, they also store more water. This is called intracellular hydration, which is beneficial for muscle function, performance, and recovery. This change in intracellular hydration status can occasionally be experienced as a visible or perceptible increase in fullness—sometimes described as puffiness or tightness, primarily in the abdomen. The best way to minimize the chances of this occurring is to take a more gradual approach to introducing a creatine-containing supplement like Qualia Creatine+. For persons wanting to take a gradual approach, consider starting with ¼ scoop for a couple of days then increase to ½ scoop for a few more days before doing a full scoop daily. Remember to also pay particular attention to thirst and hydration when beginning to supplement with creatine—it can be useful to slightly increase water intake. If you do experience bloating, digestive upset, or discomfort, reduce the amount of creatine being supplemented for several days or pause supplementation. If bloating persists while supplementing with a creatine-containing supplement, please consult a healthcare provider to rule out other causes. In rare cases, bloating could be due to unrelated digestive or medical issues.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

Creatine loading has been used as a quicker way to increase tissue levels of creatine. A typical creatine loading phase would last for 5-7 days, during which the equivalent of 4 scoops of Qualia Creatine+ would be taken, with the scoops spread throughout the day. After this loading phase there would be a maintenance phase where the amount would be reduced to a more standard creatine dose of 3-5 grams (about ½ to 1 scoop) daily to maintain creatine levels. We don’t encourage creatine loading because it can be more likely to cause digestive issues for some people, and because similar tissue levels of creatine can be achieved without having to load creatine when it is taken daily.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.